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Risk classification and door-to-antibiotic time in patients with suspected sepsis

Objective:

to evaluate the association between risk classification and door-to-antibiotic time in patients with suspected sepsis.

Method:

retrospective cohort study, with a sample of 232 patients with suspected sepsis treated at the emergency department. They were divided into 2 groups: with and without risk classification. Once the door-to-antibiotic time was identified, one-way analysis of variance was performed with Bonferroni post hoc test or independent Student’s t-test for continuous quantitative variables; Pearson correlation tests, point-biserial correlation or biserial correlation for association analyses; and bootstrap procedure when there was no normal distribution of variables. For data analysis, the Statistical Package for the Social Sciences software was used.

Results:

the door-to-antibiotic time did not differ between the group that received risk classification compared to the one that was not classified. Door-to-antibiotic time was significantly shorter in the group that received a high priority risk classification.

Conclusion:

there was no association between door-to-antibiotic time and whether or not the risk classification was performed, nor with hospitalization in infirmaries and intensive care units, or with the length of hospital stay. It was observed that the higher the priority, the shorter the door-to-antibiotic time.

Descriptors:
Sepsis; Triaje; Hospital Emergency Service; Anti-Bacterial Agents; Emergency Nursing; Critical Care


Highlights:

(1) Performing risk classification has a favorable impact on the management of sepsis.

(2) higher the clinical priority ranked, the shorter the door-to-antibiotic time.

(3) Door-to-antibiotic time did not differ between classified and unclassified groups.

(4) Assertive risk classification is more important than its implementation itself.

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E-mail: rlae@eerp.usp.br