The bullosis diabeticorum is a rare disease associated with Diabetes mellitus of long duration. The clinical manifestations are large and distended acral blisters. The differential diagnosis must be made with epidermolysis bullosa, pemphigus, bullous pemphigoid, burns, erysipelas, arthropod bites and others. The histopathology exam is not typical. The dermatologist should suspect of the disease in long-term diabetic patients of with blisters in acral locations without marked inflammation.
diabetes mellitus; diabetes mellitus, type 2; Skin diseases, Vesiculobullous
