Leukemic retinopathy

Leukemia is a systemic and heterogeneous(¹) hematological disease, with retinal involvement as the most common ocular manifestation(²). Leukemic retinopathy (Figure 1) may arise from direct infiltration or hematologic abnormalities. These manifest as intraretinal or preretinal hemorrhages and cotton-wool spots(²). Treatment resolves the retinopathy within the first 2 months(²). Management should be individualized based on the patients’ underlying medical condition(¹). If untreated, the sequelae include choroidal neovascularization and tractional retinal detachments(²).

• Informed consent was obtained from all patients included in this study.
• Funding:
  This study received no specific financial support.

REFERENCES

• ¹ Ghanbarnia M, Sedaghat S, Rasoulinejad SA. Leukemic retinopathy presenting as concurrent bilateral subhyaloid hemorrhage and subarachnoid hemorrhage in a patient with acute monocytic leukemia: a case report. J Med Case Rep. [Internet]. 2022 [cited 2024 Aug 21];16(1):466. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9758892/
  » https://pmc.ncbi.nlm.nih.gov/articles/PMC9758892/
• ² Beketova T, Mordechaev E, Murillo B, Schlesinger MD. Leukemic retinopathy: a diagnostic clue for initial detection and prognosis of leukemia. Creus [Internet]. 2023 [cited 2024 Sep 21];15(12):e50587. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10788118/
  » https://pmc.ncbi.nlm.nih.gov/articles/PMC10788118/

Publication Dates

• Publication in this collection
  21 July 2025
• Date of issue
  2025

History

• Received
  17 Dec 2024
• Accepted
  15 Jan 2025