Between January/1989 and June/1996, 1 059 carpal tunnel syndrome hands (CTS) from 668 patients were studied. None had been previously operated and all had bilateral conduction studies; peripheral neuropathy was excluded. The patients were selected with sensory median/radial difference (MRD) > or = 1.0 ms that strongly supports electrodiagnosis of CTS (standard deviation >6) after stimulation on wrist and recording on thumb. Normal MRD were obtained in 125 hands with upper limit of normality = 0,43 ms (mean + 2 SD). The age ranged from 17 to 83 years (mean 47.5) and 91.3% were female; the complaints were bilateral in 72% and nocturnal/awakening in 85.3%. Pain, numbness and paraesthesia occurred in 64.4%; pain as the only symptom was rare but proximal extension was frequent (39.4%). All fingers were symptomatic in 42.5%, followed by middle, middle-ring, thumb-index-middle and then index-middle-ring ones. There was no correlation with traumatic past history on wrist. The duration CTS symptoms ranged from 1 to > 120 months. Diabetes mellitus was present in 4.4% even after peripheral neuropathy exclusion.
carpal tunnel syndrome; median nerve; compression neuropathy; mononeuropathy
