The ideas found in the medical literature about clinical and pathological aspects concerning the Guillain-Barré syndrome are varied; the authors try in this paper to give their opinion on the subject. As far as the cranial nerves are concerned, the literature shows that the VIIth is doubtless the more frequently injured; the oculomotor and bulbar nerves are seldom damaged. This study was done in 7 patients selected from 18 cases with Guillain-Barré syndrome in the Serviço de Neurologia da Escola Paulista de Medicina. All 7 presented an albumino-cytologic dissociation in the C.S.F., a swift recovery towards cure and envolvement of the IXth and Xth nerves. One case presented isolated lesion of the IXth and Xth nerves; one case, involvement of the IXth, Xth and XIth nerves; four cases, associated lesion of the IXth, Xth and others than bulbar nerves; four cases, paralysis of the limbs besides involvement of the cranial nerves. The authors call attention to high incidence of the bulbar form of the Guillain-Barré syndrome in their material, in contrast with what has been reported in the literature (7 bulbar cases out of 18 Guillain-Barré syndrome patients).