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Procedural learning and anxiolytic effects: electroencephalographic, motor and attentional measures

The objective of the present study was to evaluate attentional, motor and electroencephalographic (EEG) parameters during a procedural task when subjects have ingested 6mg of bromazepam. The sample consisted of 26 healthy subjects, male or female, between 19 and 36 years of age. The control (placebo) and experimental (bromazepam 6mg) groups were submitted to a typewriting task in a randomized, double-blind design. The findings did not show significant differences in attentional and motor measures between groups. Coherence measures (qEEG) were evaluated between scalp regions, in theta, alpha and beta bands. A first analysis revealed a main effect for condition (Anova-2way - condition versus blocks). A second Anova 2-way (condition versus scalp regions) showed a main effect for both factors. The coherence measure was not a sensitive tool at demonstrating differences between cortical areas as a function of procedural learning.

brain mapping; qEEG; coherence; motor tranning; motor sensory integration; anxiolitics


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