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Neurological complications in patients with SARS-CoV-2 infection: a systematic review

Complicações neurológicas em pacientes infectados pelo SARS-CoV-2: uma revisão sistemática

ABSTRACT

Background:

As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations.

Objective:

To review the literature on neurological complications of SARS-CoV-2 infection.

Methods:

Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020.

Results:

A total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome.

Conclusion:

Recognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.

Keywords:
Coronavirus Infections; COVID-19; Neurology; Guillain-Barré Syndrome; Encephalitis; Stroke

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