Iki et al. (1313. Iki M, Fujita Y, Tamaki J, Kouda K, Yura A, Sato Y, et al. Trabecular bone score may improve FRAX(r) prediction accuracy for major osteoporotic fractures in elderly Japanese men: the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Cohort Study. Osteoporos Int. 2015;26(1):1841-8./A2 |
N: 2012 men over the age of 65 Country: Japan |
To assess the risk of fracture with the combination of FRAX and TBS in relation to FRAX alone. |
In total, 22 men with MOF were identified. TBS can improve FRAX MOF prediction accuracy for Japanese older men |
Schousboe et al. (1414. Schousboe JT, Vo T, Taylor BC, Cawthon PM, Schwartz AV, Bauer DC, et al. Prediction of incident major osteoporotic and hip fractures by trabecular bone score (TBS) and prevalent radiographic vertebral fracture in older men. J Bone Miner Res. 2016;31(3):690-7./A1 |
N: 5979 men over the age of 65 -Country: USA |
To assess the association between TBS and incident fractures in men independent of the prevalence of radiographic vertebral fracture. |
TBS and the prevalent radiographic vertebral fracture are associated with large osteoporosis fractures incident in older men, independent of each other. |
Su et al. (1515. Su Y, Leung J, Hans D, Aubry-Rozier B, Kwok T. Added clinical use of trabecular bone score to BMD for major osteoporotic fracture prediction in older Chinese people: the Mr. OS and Ms. OS cohort study in Hong Kong. Osteoporos Int. 2017;28(1):151-60./A2 |
N: 2000 men over the age of 65 Country: China |
To validate and recommend practical TBS thresholds for predicting fractures in the older population |
TBS in combination with BMD can predict MOF more reliably in older men than BMD alone. |
Schousboe et al. (1616. Schousboe JT, Vo T, Langsetmo L, Taylor BC, Cawthon PM, Schwartz AV, et al. Association of trabecular bone score (TBS) with incident clinical and radiographic vertebral fractures adjusted for lumbar spine BMD in older men: a prospective cohort study. J Bone Miner Res. 2017;32(7):1554-8./B1 |
N: 5831 men over the age of 65 -Country: USA |
To evaluate the association of TBS with clinical and radiographic vertebral fractures in older men |
TBS is not associated with incidental vertebral fracture in older men when adjusted for the age and BMD of the lumbar spine; the study leaves open this association with clinical vertebral fractures. The study reinforces the influence of BMI on the calculation of TBS. |
Anderson et al. (1717. Anderson KB, Holloway-Kew KL, Mohebbi M, Kotowicz MA, Hans D, Pasco JA. Is trabecular bone score less affected by degenerative-changes at the spine than lumbar spine BMD? Arch Osteoporos. 2018;13(1):127./B1 |
N: 728 Country: Australia |
To investigate whether the presence of degenerative changes in the spine in older men affects TBS in the same way that they affect BMD. |
This study suggests that TBS is less affected by degenerative changes in the spine than BMD. Thus, TBS may be useful in assessing the risk of fractures in men with degenerative changes in the spine. |