This study aimed to verify the influence of colostrum in serum biochemical parameters in newborn lambs. Blood samples were taken of 28 lambs, determining the protein, energy and kidney function indicators, bilirrubins and the enzymes aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT) and creatine kinase (CK), in pre and post-colostrum moments. The data were analyzed comparing the variability of the parameters between the two moments. There was an elevation (P<0.001) in total protein concentrations, in response to substantial increase (P<0.01) in total globulin levels, and a slight decrease (P<0.05) in albumin concentration, after colostral intake. We also observed higher values of total and conjugated bilirubins (P<0.001), and variation of kidney metabolites, with an elevation of urea levels (P<0.01) concomitant to decrease of creatinine values (P<0.001) in the post-colostrum moment. There was an increase (P<0.001) in glycemia, total cholesterol and triglycerides, as well as of the enzymatic activities (P<0.001) of AST and GGT, between the moments evaluated. In conclusion, the dynamics of biochemical profile in newborn lambs suffers the effect of colostrum intake and of adaptations of physiological functions to extrauterine life. The parameters values vary markedly in the postnatal period, being recommended to use proper reference values for this phase.
blood; clinical biochemistry; neonate; nursing; sheep