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Publicação de: Instituto Israelita de Ensino e Pesquisa Albert Einstein
Área: Ciências Da Saúde
Versão impressa ISSN: 1679-4508
Versão on-line ISSN: 2317-6385
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Sumário

einstein (São Paulo), Volume: 24, Número: spe3, Publicado: 2026

einstein (São Paulo), Volume: 24, Número: spe3, Publicado: 2026

Document list
Documents
Case Report
Severe bleeding diathesis after dental extractions: a complex case of coagulation disturbances in a patient with multiple myeloma Eduardo, Fernanda de Paula Bezinelli, Leticia Mello Goes, Vitor Abreu de Ferreira, Mariana Henriques Gobbi, Marcella Ferreira Bergamin, Livia Goron Kutner, José Mauro Corrêa, Luciana Bonamigo-Filho, Jose Luiz

Resumo em Inglês:

ABSTRACT This case report describes a male patient diagnosed with multiple myeloma who experienced significant bleeding from both the maxillary and mandibular dental sockets following dental extraction, lasting several days. Laboratory tests revealed prolonged prothrombin time and thrombin time, accompanied by reduced factor VII levels. Initial management with intravenous vitamin K and fresh frozen plasma failed to achieve hemostasis. Despite the risk of thrombosis, low-dose tranexamic acid was initiated, resulting in effective hemorrhage control and improved healing of the alveolar sockets. This case illustrates the complex hemostatic imbalance between pro- and anticoagulant factors in a patient with multiple myeloma. It also underscores the diagnostic and therapeutic challenges associated with managing bleeding in patients with a high risk of thrombosis.
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Instituto Israelita de Ensino e Pesquisa Albert Einstein Avenida Albert Einstein, 627/701 , 05651-901 São Paulo - SP, Tel.: (55 11) 2151 0904 - São Paulo - SP - Brazil
E-mail: revista@einstein.br
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