Urine hepcidin, netrin-1, neutrophil gelatinase-associated lipocalin and C-C motif chemokine ligand 2 levels in multicystic dysplastic kidney

Nuran Cetin Correspondence to: Nuran Cetin E-mail: nurancetin17@hotmail.com

Eskisehir Osmangazi University, Faculty of Medicine, Department of Pediatric Nephrology, Turkey.

Zeynep Kusku Kiraz

Eskisehir Osmangazi University, Faculty of Medicine, Department of Biochemistry, Turkey.

Nadide Melike Sav

Eskisehir Osmangazi University, Faculty of Medicine, Department of Pediatric Nephrology, Turkey.

AUTHOR’S CONTRIBUTION

All authors contributed to the design and development of the study, collection, analysis and interpretation of the data, writing of the article or in its critical revision and approval of the final version.

CONFLICT OF INTEREST

The authors declare that they have no conflict of interest.

	Patients (n = 32)	Control group (n = 25)	p
Age (years)	7.5 (3.25-13)	8 (5-9.5)	0.881
Female gender (n, %)	19 (59.4%)	9 (36%)	0.082
Phosphorus (mg/dL)	4.9 ± 0.89	5 ± 0.76	0.561
Creatinine (mg/dL)	0.53 ± 0.23	0.4 ± 0.13	0.031
TPR (%)	94.6 ± 3.98	94.3 ± 2.66	0.213
ACR (mg/g)	11.4 (4.6-23.72)	6.35 (2.92-10.9)	0.037
Protein-to creatinine ratio	0.18 (0.12-0.33)	0.15 (0.11-0.18)	0.511
GFR (mL/min/1.73 m²)	140.6 ± 28.33	175.8 ± 29.69	0.000
Urine netrin-1(pg/mg creatinine)	0.26 (0.13-0.55)	0.14 (0.11-0.21)	0.041
Urine hepcidin (ng/mg creatinine)	0.35 (0.26-0.67)	0.45 (0.25-0.56)	0.502
Urine MCP-1/CCL-2 (pg/mg creatinine)	0.13 (0.04-0.33)	0.08 (0.03- 0.24)	0.543
Urine NGAL (ng/mg creatinine)	0.2 (0.13-0.36)	0.22 (0.13-0.35)	0.672

Brasil