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Microscopic polyangiitis with diffuse alveolar hemorrhage

Microscopic Polyangiitis is a form of Anti-Neutrophil Cytoplasmic Antibody (ANCA)- associated small-vessel vasculitis that preferentially involves venules, capillaries and arterioles and may also involve arteries and veins. It is one of the most common primary systemic small-vessel vasculitis. Its clinical presentation is not distinguishable from the Wegener’s granulomatosis (WG) and the Churg-Strauss syndrome (CSS). These types of small-vessel vasculitis are histologically similar and can be differentiated by the presence of granulomatous inflammation in WG or asthma in CSS. The case of a 66-year-old man with microscopic polyangiitis presenting with alveolar hemorrhage is reported with a discussion of the differential diagnosis of other types of pulmonary small-vessel vasculitis.

Microscopic polyangiitis; Alveolar hemorrhage; Pulmonary vasculitis


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