A comparative analysis of transcranial Doppler parameters acquired during carotid stenting and semi-eversion carotid endarterectomy

Olveira, Germano da Paz; Guillaumon, Ana Terezinha; Benvindo, Sérgio Clementino; Lima, Joana Mayra Teixeira; Barreto, Sérgio Ricardo Freire; Avelar, Wagner Mauad; Cendes, Fernando

doi:10.1590/1677-5449.003316

Germano da Paz Olveira ^**Correspondence Germano da Paz Oliveira Rua José Olímpio de Melo, 2436/102 - Ilhotas CEP 64014-063 - Teresina (PI) - Brazil Tel.: +55 (86) 99982-0901 E-mail: germanooliveira@hotmail.com

Universidade Estadual de Campinas – UNICAMP, Departamento de Cirurgia, Campinas, SP, Brazil.

Ana Terezinha Guillaumon

Universidade Estadual de Campinas – UNICAMP, Departamento de Cirurgia, Campinas, SP, Brazil.

Sérgio Clementino Benvindo

Centro Universitário Uninovafapi, Teresina, PI, Brazil.

Joana Mayra Teixeira Lima

Universidade Federal do Piauí – UFPI, Teresina, PI, Brazil.

Sérgio Ricardo Freire Barreto

Universidade Estadual de Campinas – UNICAMP, Departamento de Neurologia, Campinas, SP, Brazil.

Wagner Mauad Avelar

Universidade Estadual de Campinas – UNICAMP, Departamento de Neurologia, Campinas, SP, Brazil.

Fernando Cendes

Universidade Estadual de Campinas – UNICAMP, Departamento de Neurologia, Campinas, SP, Brazil.

Conflicts of interest: No conflicts of interest declared concerning the publication of this article.

*Correspondence Germano da Paz Oliveira Rua José Olímpio de Melo, 2436/102 - Ilhotas CEP 64014-063 - Teresina (PI) - Brazil Tel.: +55 (86) 99982-0901 E-mail: germanooliveira@hotmail.com

Author information

GPO - Vascular and endovascular surgeon from Universidade Estadual de Campinas (UNICAMP); MSc in Sciences from UNICAMP; Primary physician at Serviço de Cirurgia Vascular, Hospital Universitário do Piauí and Hospital Getúlio Vargas.

ATG - Vascular and endovascular surgeon; PhD, tenured professor at Departamento de Cirurgia, Universidade Estadual de Campinas (UNICAMP); Chief of the Discipline of Peripheral Vascular Diseases, UNICAMP; Coordinator, Serviço de Alta Complexidade em Cirurgia Vascular e Endovascular, UNICAMP.

SCB - Medical student, Centro Universitário Uninovafapi.

JMTL - MD from Universidade Federal do Piauí (UFPI); Resident physician of Pediatrics at Universidade de São Paulo (USP).

SRFB - General surgeon and critical care physician from Universidade Estadual de Campinas (UNICAMP); Primary physician at the intensive care units of Centro de Apoio à Saúde da Mulher and Hospital de Clínicas da UNICAMP; Collaborating physician at Laboratório de Hemodinâmica Cerebral, UNICAMP.

WMA - Neurologist from Universidade Estadual de Campinas (UNICAMP); PhD in Medical Pathophysiology from UNICAMP; Collaborating primary physician at Ambulatório de Neurologia Vascular – Hospital de Clínicas da UNICAMP; head of Laboratório de Hemodinâmica Cerebral, UNICAMP.

FC - Neurologist from Universidade Estadual de Campinas (UNICAMP); PhD, tenured professor at Departamento de Neurologia da UNICAMP; Coordinator, Subcomissão de Pós-Graduação, Curso de Fisiopatologia Médica; Member, Comissão de Pesquisa da FCM-UNICAMP.

Author contributions

Conception and design: GPO, ATG, WMA, FC

Analysis and interpretation: GPO, ATG, FC

Data collection: GPO, ATG, SCB, JMTL, SRFB, WMA, FC

Writing the article: GPO, ATG, SRFB, WMA, FC

Critical revision of the article: GPO, ATG, SRFB, WMA, FC

Final approval of the article*: GPO, ATG, SCB, JMTL, SRFB, WMA, FC

Statistical analysis: GPO, ATG, WMA, FC

Overall responsibility: GPO, ATG

*All authors have read and approved of the final version of the article submitted to J Vasc Bras.

Variables	CEA (n = 17)	CAS (n = 16)	Total (n = 33)	*p-value*
Male	15 (88.2%)	14 (87.5%)	29 (87.8%)	1.000^* * Fisher test;
Diabetes	6 (35.3%)	9 (56.2%)	15 (45.4%)	0.226^† † chi-square test.
Smoking history < 1 year	3 (17.6%)	3 (18.7)	6 (18.2%)	1.000^* * Fisher test;
Hypertension	15 (88.2%)	12 (75%)	27 (81.8%)	0.398^* * Fisher test;
Dyslipidemia	7 (41.2%)	10 (62.5%)	17 (51.5%)	0.220^† † chi-square test.
Renal insufficiency	0 (0%)	1 (6.2%)	1 (3.0%)	-
Smoking history > 1 year	11 (64.7%)	11 (68.7%)	22 (66.7%)	0.805^† † chi-square test.
CAD	5 (29.4%)	11 (68.7%)	16 (48.5%)	0.023^† † chi-square test.
Right-sided lesion	10 (58.8%)	6 (37.5%)	16 (48.5%)	0.220^† † chi-square test.
Total contralateral obstruction	1 (5.9%)	4 (25%)	5 (15.1%)	0.192^* * Fisher test;
70-99% contralateral obstruction	1 (5.9%)	2 (12.5%)	3 (9.1%)	0.192^* * Fisher test;
Symptomatic	7 (41.2%)	6 (37.5%)	13 (39.4%)	0.829^† † chi-square test.
General anesthesia	16 (94.1%)	8 (50%)	24 (72.7%)	0.006^* * Fisher test;

Groups Variables	CEA (n = 17)					CAS (n = 16)					p-value ^* * Mann-Whitney test.
Groups Variables	Mean	SD	Min	Med	Max	Mean	SD	Min	Med	Max	p-value ^* * Mann-Whitney test.
Age (years)	71.5	5.6	63	69	81	70.9	7.1	54	72.5	78	0.772
Protection time (s)	1016.5	343.7	540	1020	2160	881	309.2	393	799.5	1360	0.357
Number of MES	89.8	171.4	5	46	745	597.5	343.3	172	610.5	1640	<0.0001
MBP variation (mmHg)	22.6	8	10	23	35	21.1	10.7	5	21	40	0.563
Duration of ischemia (s)	0	0	0	0	0	33.8	83.4	0	0	312	-

Groups Protection stage	CEA (n = 17)					CAS (n = 16)					p-value ^* * Comparison between groups using the ANOVA test;
Groups Protection stage	Mean	SD	Min	Med	Max	Mean	SD	Min	Med	Max
Pre-protection	51.6	146	0	13	615	291.8	275.1	16	210	1125	<0.0001
During protection	16.6	23	0	8	74	230.1	125.1	99	167,5	494	<0.0001
Post-protection	22.2	18.9	2	15	60	75.6	80.8	0	53	312	0.009
Total^† † Comparison between the protection stages using the ANOVA test: for the CEA group, there was no statistical difference between the stages; for the CAS group, p < 0.0001 for pre-protection versus post-protection, and for during protection versus post-protection, but no statistical difference between pre-protection and during protection.	89.8	171.4	5	46	745	597.5	343.3	172	610.5	1640	<0.0001

Groups Protection stage	CEA (n = 17)					CAS (n = 16)					p-value ^* * Comparison between groups using the ANOVA test;
Groups Protection stage	Mean	SD	Min	Med	Max	Mean	SD	Min	Med	Max
Pre-protection	37.9	8.7	21	36	55	48.4	12.5	31	45.5	78	0.152
During protection	35.7	14.9	11	34	69	39.1	12.2	24.1	38.2	72.5	0.152
Post-protection	48.3	15.3	27	45	85	50	27	0.8	48.5	110	0.152
p-value^† † Comparison between protection stages using the ANOVA test.	<0.0001					<0.0001					-

[1] Conflicts of interest: No conflicts of interest declared concerning the publication of this article.

Brasil

Brasil

A comparative analysis of transcranial Doppler parameters acquired during carotid stenting and semi-eversion carotid endarterectomy

Uma análise comparativa de parâmetros do Doppler transcraniano adquiridos durante a colocação de stent carotídeo e endarterectomia carotídea por semieversão

Abstract

Background

Objective

Method

Results

Conclusion