Among 420 patientes found with diverse subacute and chronic neuropathies, 22 were diagnosed as cases of true trypanosomic encephalopathy by means of the demonstration of parasites in blood (by xenodiagnosis or hemoculture) or through serologic tests. In 50% or more of those patientes, following semiologic elements were prevalente: dysprosexia and depression in 81.8%; cephalea and confusion in 72.7%; weakness of muscular-tendineous reflexes and speech disturbance in 63.6% dispraxies in 59.0%; disturbances of gait and myoclonic crises in 54.5%; bradikinesias in 59.0%. Other symptoms were verified in a mirror scale: paresias, delirant ideas, cerebral pertubation, dizziness fits, diplopia, lipothymes, fluctuant humour, disautonomic syndrome and excitation. In 8 patients a clinically perceptible cardiopathy was verified and in 2 digestive problems were found. A discussion of the facts already exposed about the chagasic chronic encephalopathy in comparison to the findings of other authors is carried out.