First Thousand Days of Child Life and the Development of Risk Factors for Malocclusions

Traebert, Eliane; Schneider, Ione Jayce Ceola; Lunardelli, Sandra Espíndola; Lunardelli, Abelardo Nunes; Martins, Luiz Gustavo Teixeira; Traebert, Jefferson

doi:10.1590/pboci.2023.054

Eliane Traebert

Conceptualization

Methodology

Formal Analysis

Investigation

Data Curation

Writing - Original Draft and Writing - Review and Editing

critical review of intellectual content and approval of the final version to be published

Postgraduate Program in Health Sciences, University of South Santa Catarina, Palhoça, SC, Brazil

School of Medicine, University of South Santa Catarina, Palhoça, SC, Brazil

https://orcid.org/0000-0001-9667-7216

Ione Jayce Ceola Schneider

Methodology

Data Curation

Writing - Original Draft and Writing - Review and Editing

critical review of intellectual content and approval of the final version to be published

Postgraduate Program in Rehabilitation Science, Public Health and Neuroscience, Federal University of Santa Catarina, Araranguá, SC, Brazil

https://orcid.org/0000-0001-6339-7832

Sandra Espíndola Lunardelli

Methodology

Formal Analysis

Investigation

Writing - Original Draft and Writing - Review and Editing

critical review of intellectual content and approval of the final version to be published

Postgraduate Program in Health Sciences, University of South Santa Catarina, Palhoça, SC, Brazil

https://orcid.org/0000-0002-7836-6083

Abelardo Nunes Lunardelli

Methodology

Formal Analysis

Investigation and Writing - Review and Editing

critical review of intellectual content and approval of the final version to be published

Postgraduate Program in Health Sciences, University of South Santa Catarina, Palhoça, SC, Brazil

https://orcid.org/0000-0002-3052-8020

Luiz Gustavo Teixeira Martins

Methodology

Data Curation and Writing - Review and Editing

critical review of intellectual content and approval of the final version to be published

Postgraduate Program in Health Sciences, University of South Santa Catarina, Palhoça, SC, Brazil

https://orcid.org/0000-0003-0898-1440

Jefferson Traebert Correspondence: Jefferson Traebert, Av. Pedra Branca, 25, Cidade Universitária, Pedra Branca, Palhoça, SC, Brazil. 88132270. E-mail:jefferson.traebert@gmail.com

Conceptualization

Methodology

Formal Analysis

Investigation

Data Curation

Writing - Original Draft and Writing - Review and Editing

critical review of intellectual content and approval of the final version to be published

Postgraduate Program in Health Sciences, University of South Santa Catarina, Palhoça, SC, Brazil

https://orcid.org/0000-0002-7389-985X

Correspondence: Jefferson Traebert, Av. Pedra Branca, 25, Cidade Universitária, Pedra Branca, Palhoça, SC, Brazil. 88132270. E-mail:jefferson.traebert@gmail.com

Conflict of Interest

The authors declare no conflicts of interest.

Variables	PRc	CI 95%	p-value	PRa	CI 95%	p-value
Mother schooling at birth			0.01			0.02
> 8 years	1.00			1.00
≤ 8 years	1.41	1.06; 1.88		1.58	1.07; 2.37
Stable partner at birth			0.20			0.89
Yes	1.00			1.00
No	1.36	0.87; 2.13		0.05	0.50; 2.22
Smoking at pregnancy			0.03			0.23
No	1.00			1.00
Yes	1.45	1.03; 2.02		1.32	0.82; 2.11
Birth weight			0.14			0.93
≥ 2,500g	1.00			1.00
< 2,499g	1.53	0.90; 2.60		1.04	0.38; 2.86
Apgar 1st min			0.03			0.08
≥ 8	1.00			1.00
< 7	0.35	0.12; 1.04		0.39	0.13; 1.15
Antibiotic use by child in the first two years			0.04			0.07
No	1.00			1.00
Yes	1.36	1,01; 1.85		1.49	0.97; 2.28
Child medicine using for more than 30 consecutive days			0.15			0.99
Yes	1.00			1.00
No	0.78	0.56; 1.08		1.00	0.60; 1.67
Child hospitalization for more than two days in the first two years			0.20			0.42
No	1.00			1.00
Yes	0.80	0.57; 1.11		1.24	0.73; 2.11

Variables	PRc	CI 95%	p-value	PRa	CI 95%	p-value
Occupation of mother at birth			<0.01			0.03
No income	1.00			1.00
With income	1.32	1.12; 1.57		1.26	1.02; 1.56
Occupation of father at birth			0.12			0.04
With income	1.00			1.00
No income	1.32	0.97; 1.78		1.46	1.01; 2.14
Stable partner at birth			0.11			0.95
Yes	1.00			1.00
No	1.27	0.98; 1.65		1.02	0.60; 1.72
Smoking at pregnancy			0.14			0.34
No	1.00			1.00
Yes	1.18	0.96; 1.46		1.13	0.87; 1.47
Drug use during pregnancy			0.10			0.40
No	1.00			1.00
Yes	1.59	1.11; 2.28		1.30	0.70; 2.43
Infectious diseases in pregnancy			0.02			0.14
No	1.00			1.00
Yes	1.22	1.03; 1.45		1.16	0.95; 1.43
Nursery attendance in the first two years			<0.01			0.10
No	1.00			1.00
Yes	1.29	1.07; 1.55		1.20	0.97; 1.48
Antibiotic use by child in the first two years			<0.01			0.28
No	1.00			1.00
Yes	1.29	1.07; 1.55		1.14	0.89; 1.46
Infectious diseases in child in the first two years			0.05			0.64
No	1.00			1.00
Yes	1.28	0.97; 1.68		1.08	0.77; 1.53
Reflux in the child in the first two years			0.06			0.34
No	1.00			1.00
Yes	1.23	1.01; 1.50		1.13	0.88; 1.46

Variables	PRc	CI 95%	p-value	PRa	CI 95%	p-value
Father schooling at birth			0.36			0.41
> 8 years	1.00			1.00
≤ 8 years	0.95	0.86; 1.05		0.95	0.86; 1.06
Occupation of mother at birth			0.11			0.74
No income	1.00			1.00
With income	1.06	0.98; 1.15		1.01	0.91; 1.13
Stable partner at birth			0.10			0.48
Yes	1.00			1.00
No	1.12	1.00; 1.26		1.11	0.83; 1.48
Pregnancy age			<0.01			0.03
≥ 20 years	1.00			1.00
10 to 19 years	0.84	0.75; 0.96		0.83	0.70; 0.98
Smoking at pregnancy			0.10			0.92
No	1.00			1.00
Yes	1.09	0.99; 1.20		1.00	0.99; 1.15
Alcohol use during pregnancy			0.07			0.28
No	1.00			1.00
Yes	1.16	1.03; 1.29		1.09	0.92; 1.29
Nursery attendance in the first two years			<0.01			0.01
No	1.00			1.00
Yes	1.14	1.05; 1.25		1.15	1.02; 1.28
Infectious diseases in child in the first two years			0.01			0.15
No	1.00			1.00
Yes	1.20	1.04; 1.38		1.14	0.95; 1.36
Antibiotic use by child in the first two years			0.01			0.81
No	1.00			1.00
Yes	1.11	1.00; 1.22		1.01	0.90; 1.13

Variables	PRc	CI 95%	p-value	PRa	CI 95%	p-value
Occupation of mother at birth No income	1.00		0.01	1.00		0.34
With income Pregnancy age	1.23	1.04; 1.44	0.03	1.10	0.89; 1.37	0.38
≥ 20 years 10 to 19 years	1.00 0.79	0.63; 0.99		1.00 0.87	0.65; 1.17
Number of prenatal appointments ≥ 6	1.00		0.10	1.00		0.31
< 5 Smoking at pregnancy	1.23	0.98; 1.56	0.02	1.15	0.83; 1.59	0.09
No Yes	1.00 1.27	1.05; 1.53		1.00 1.22	0.96; 1.56
Nursery attendance in the first two years No	1.00		0.02	1.00		0.03
Yes Hospitalization in the first 29 days	1.22	1.02; 1.45	0.01	1.27	1.01; 1.59	0.05
No Yes	1.00 1.48	1.17; 1.88		1.00 1.34	1.01; 1.80
Reflux in the child in the first two years No	1.00		<0.01		1,00	0.05
Yes Infectious diseases in child in the first two years	1.31	1.09; 1.57	0.03	1.30	1.01; 1.70	0.70
No Yes	1.00 1.28	0.99; 1.66		1.00 0.93	0.67; 1.30
Child medicine using for more than 30 consecutive days No 1.00			0.10	1.00		0.75
Yes Antibiotic use by child in the first two years	1.18	0.98; 1.42	<0.01	0.95	0.73; 1.24	0.19
No Yes	1.00 1.31	1,10; 1.57		1.00 1.18	0.91; 1.52

	Digital Suction
Variables	No	Yes	p-value
	N (%)	N (%)
Mother schooling at birth (n=655)			0.20
≤ 8 years	172 (89.5)	20 (10.5)
> 8 years	386 (92.5)	31 (7.5)
Father schooling at birth (n=609)			0.81
≤ 8 years	198 (92.1)	17 (7.9)
> 8 years	280 (91.5)	26 (8.5)
Occupation of mother at birth (n=641)			0.08
With income	288 (89.1)	35 (10.9)
No income	247 (77.4)	71 (22.6)
Occupation of father at birth (n=614)			0.72
With income	533 (90.9)	53 (9.1)
No income	26 (92.9)	2 (7.1)
Stable partner at birth (n=640)			0.79
No	44 (89.8)	5 (10.2)
Yes	538 (91.0)	53 (9.0)
Nursery attendance in the first two years (n=566)			0.25
Yes	302 (93.2)	22 (6.8)
No	219 (90.5)	23 (9.5)
Pregnancy age (n=641)			0.80
10 to 19 years	119 (91.5)	11 (8.5)
≥ 20 years	464 (90.8)	47 (9.2)
Number of prenatal appointments (n=589)			0.63
≥ 6	485 (90.8)	49 (9.2)
< 5	51 (92.7)	4 (7.3)
Alcohol use during pregnancy (n=629)			0.06
Yes	34 (82.3)	7 (17.7)
No	537 (91.3)	51 (8.7)
Smoking at pregnancy (n=636)			0.07
Yes	81 (86.2)	13 (13.8)
No	498 (91.9)	44 (8.1)
Drug use during pregnancy (n=642)			0.99
Yes	10 (90.9)	1 (9.1)
No	574 (90.9)	57 (9.1)
Infectious diseases in pregnancy (n=611)			0.84
No	346 (91.4)	21 (8.6)
Yes	214 (91.8)	30 (8.2)
Gestational age (n=499)			0.74
< 37 weeks	27 (86.7)	4 (13.3)
37 to 41 weeks	349 (90.2)	38 (9.8)
≥ 42 weeks	27 (87.6)	4 (12.9)
Way of delivery (n=491)			0.72
Cesarean	183 (90.1)	20 (9.9)
Vaginal	257 (89.2)	31 (10.8)
Child gender (n=655)			0.71
Male	302 (90.1)	24 (9.9)
Female	302 (89.1)	27 (10.9)
Birth weight (n=479)			0.63
< 2,499g	24 (92.3)	2 (7.7)
≥ 2,500g	405 (89.4)	48 (10.6)
Apgar 1st min (n=395)			0.33
< 7	27 (87.1)	4 (12.9)
≥ 8	334 (91.7)	30 (8.3)
Reflux in the child in the first two years (n=642)			0.06
Yes	80 (85.1)	13 (14.9)
No	504 (91.8)	45 (8.2)
Infectious diseases in child in the first two years (n=572)			0.84
Yes	433 (91.1)	42 (8.9)
No	89 (91.8)	8 (8.2)
Child antibiotic using for more than 30 consecutive days (n=633)			0.23
Yes	359 (89.9)	40 (10.1)
No	217 (92.7)	17 (7.3)
Child medicine using for more than 30 consecutive days (n=641)			0.50
Yes	95 (89.5)	11 (10.5)
No	490 (91.6)	45 (8.4)
Child hospitalization for more than two days in the first two years (n=650)			0.72
No	535 (90.3)	10 (9.7)
Yes	58 (91.4)	47 (8.6)
Hospital admission of the child in the first 29 days (n=491)			0.37
No	451	5 (14.7)
Yes	32	3 (9.9)

[1] Correspondence: Jefferson Traebert, Av. Pedra Branca, 25, Cidade Universitária, Pedra Branca, Palhoça, SC, Brazil. 88132270. E-mail:jefferson.traebert@gmail.com

Brasil

Brasil

First Thousand Days of Child Life and the Development of Risk Factors for Malocclusions

ABSTRACT

Objective:

Material and Methods:

Results:

Conclusion: