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Results of keloids treatment with surgery and iniquimod 5% cream: a prospective study

INTRODUCTION: The treatment of keloids represents a therapeutic challenge, with results often disappointing. More effective adjuvant therapies are needed to reduce high rates of relapse. This research is based on a combined modality with application of imiquimod 5% cream combined with surgery, having as objective the evaluation of treatment and recurrence of keloid scar. METHODS: This prospective study evaluated 14 patients at a total of 25 keloids, with a minimum follow up of 6 months. Intralesional excision was performed and initiated the application of imiquimod 5% cream on the day of surgery and continued for two months. The evaluation of the scar was analyzed by an Assessment Scale (patient and an observer - ruler of service Plastic Surgery), signs of relapse and also the size of the scar in the pre-and postoperatively. RESULTS: After 6 months of follow up, patients showed an improvement of 72% and 88% in the ruler's analysis, with a recurrence rate of 8% and reduction of scar area (p = 0.0053). CONCLUSION: The use of Imiquimode 5% cream in the post surgery for resection of the keloid recurrence decreased significantly in their evaluation of 6 months.

Keloid; Recurrence; Aminoquinolinaes


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