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Production of knowledge: genetic basis, biochemical and immunological of Meares-Irlen Syndrome

ABSTRACT

Meares-Irlen syndrome, deficiency of the visual processing identified in individuals with dyslexia can be defined as a visual perceptive disorder that is believed to be originated in the primary visual cortex. This study deals with an integrative literature review aimed to analyze the scientific production in relation to biochemical, genetic and immunological basis that maybe understood in this condition. Data were obtained via online query the databases of the Virtual Health Library (VHL) that interconnects several reference databases such as SciELO (Scientific Electronic Library Online), (Latin American and Caribbean Literature Rev Sciences health), MEDLINE (International Literature on Health Sciences), and the Digital Library of UFMG. A total of 16 articles, falling between 1996 and 2014 who met the inclusion criteria were included in the proposed study. Many studies have suggested an association of the syndrome with biochemical and genetic alterations. Some support the hypothesis that immune changes and metabolism of fatty acids are involved in cognitive and learning problems. Despite the scarce volume of studies on the subject, there is increasing evidence that there is a biochemical basis involved in a variety of visual disorders and learning.

Keywords:
Dyslexia; Cholesterol; Perceptual disorders; Immunology; Genetics; Heredity

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