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Amniotic membrane transplantation for ocular surface burns

Transplante de membrana amniótica em queimaduras da superfície ocular

ABSTRACT

Objective:

To analyze the morphological and functional long-term outcomes of amniotic membrane transplantation after ocular surface chemical burns.

Methods:

This prospective study analyzed 7 patients who suffered from severe ocular surface burn and underwent amniotic membrane transplantation from 2015 to 2020 in Hospital de Clínicas - Universidade Federal do Paraná.

Results:

Out of the seven patients, six (85.7%) suffered unilateral burn and one (14.3%) suffered bilateral burn. Five of them had alkali burns (71.4%), one had acid burn (14.3%) and one suffered gunpowder fireworks burn (14.3%). Mean age was 29.4 years (±standard deviation 13.3, range 14.0 to 47.0 years). Mean visual acuity at first presentation was 1.83±0.79 logMAR (0.015 decimal) and mean VA after a follow-up of 1 year was 0.85±0.70 logMAR (0.141 decimal). The visual acuity significantly improved from 1.83±0.79 to 0.85±0.70 logMAR (p<0.05).

Conclusion:

Amniotic membrane transplantation is an effective adjunctive treatment in the management of ocular surface chemical burns with potential to improve the final vision outcome.

Keywords:
Amnion/transplantation; Eye burns; Anterior eye segment; Membranes/transplantation; Chemical burns

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