Investigación de un brote de enfermedad compatible con escorbuto en una penitenciaría masculina en el estado de Ceará, Brasil, 2019-2020: un estudio de casos y controles

Freitas, Leonardo José Alves de; Camelo, Fernanda Sindeaux; Borges, Maria Júlia Araújo; Gomes, Ricristhi Gonçalves de Aguiar; Almeida, Magda Moura de; Silva, Danniely Carolinne Soares da; Garcia, Márcio Henrique de Oliveira; Santos, Elizabeth David dos

Leonardo José Alves de Freitas

concept and design

data collection

analysis and interpretation

drafting and reviewing

integrity

Ministério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do Sistema Único de Saúde, Brasília, DF, Brazil

https://orcid.org/0000-0002-4414-8002

Fernanda Sindeaux Camelo

concept and design

data collection

analysis and interpretation

drafting and reviewing

integrity

Ministério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do Sistema Único de Saúde, Brasília, DF, Brazil

https://orcid.org/0000-0002-1680-2310

Maria Júlia Araújo Borges

analysis and interpretation

drafting and reviewing

integrity

Secretaria da Saúde do Ceará, Secretaria Executiva de Vigilância em Saúde, Fortaleza, CE, Brazil

https://orcid.org/0000-0002-9787-354X

Ricristhi Gonçalves de Aguiar Gomes

analysis and interpretation

drafting and reviewing

integrity

Secretaria da Saúde do Ceará, Secretaria Executiva de Vigilância em Saúde, Fortaleza, CE, Brazil

https://orcid.org/0000-0003-2392-0523

Magda Moura de Almeida

analysis and interpretation

drafting and reviewing

integrity

Universidade Federal do Ceará, Departamento de Saúde Comunitária, Fortaleza, CE, Brazil

https://orcid.org/0000-0002-4806-2345

Danniely Carolinne Soares da Silva

analysis and interpretation

drafting and reviewing

integrity

Ministério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do Sistema Único de Saúde, Brasília, DF, Brazil

https://orcid.org/0000-0001-9665-4196

Márcio Henrique de Oliveira Garcia

concept and design

data collection

interpretation

drafting and reviewing

integrity

Ministério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do Sistema Único de Saúde, Brasília, DF, Brazil

https://orcid.org/0000-0002-9001-278X

Elizabeth David dos Santos

concept and design

data collection

interpretation

drafting and reviewing

integrity

Ministério da Saúde, Coordenação-Geral de Vigilância de Zoonoses e Doenças de Transmissão Vetorial, Brasília, DF, Brazil

https://orcid.org/0000-0002-7045-1590

Correspondence:
Leonardo José Alves de Freitas.
e-mail:
leonardojoseph2@hotmail.com

CONFLICTS OF INTEREST

The authors have no conflicts of interest to declare.

AUTHOR CONTRIBUTIONS

Freitas LJA and Camelo FS contributed to the study concept and design, data collection, analysis and interpretation of the results, drafting and critically reviewing the contents of the manuscript. Borges MJA, Gomes RGA, Almeida MM and Silva DCS contributed to data analysis and interpretation, drafting and critically reviewing the contents of the manuscript. Garcia MHO and Santos ED contributed to the study concept and design, data collection, interpretation of the results, drafting and critically reviewing the contents of the manuscript. All the authors have approved the final version of the manuscript and are responsible for all aspects thereof, including the guarantee of its accuracy and integrity.

Associate editor:

Taís Freire Galvão - http://orcid.org/0000-0003-2072-4834

Characteristics	Cases n = 62	Controls n = 72
Race/skin color
Mixed race	47	57
White	14	14
Black	1	1
Schooling
Elementary education	41	52
Illiterate	17	6
High school education	4	12
Higher education	-	2
Age group (last birthday)
20-29	9	30
30-39	22	31
40-49	16	11
50-59	12	-
60-65	3	-
Signs and symptoms
Edema in lower limbs	62	-
Pain in lower limbs	62	-
Difficulty in walking	57	-
Hematoma/ecchymosis in lower limbs	56	-
Fever	55	-
Asthenia	54	-
Stiffness in lower limbs	51	-
Hyporexia	45	-
Signs of inflammation in lower limbs	42	-
Bleeding gums	30	-

Variable	n	Crude OR^a (95%CI^c)	p-value^d	Adjusted OR^b (95%CI^c)	p-value^d
Age (last birthday)
> 40	61	4.41 (2.13;9.14)	< 0.001	1.10 (1.05;1.17)	0.001
≤ 40	73	1.00
Working in the prison
Yes	36	0.19 (0.08;0.47)	< 0.001	0.11 (0.03;0.36)	< 0.001
No	98	1.00
Taking part in classes in the prison
Yes	45	0.24 (0.11;0.54)	< 0.001	0.21 (0.08;0.59)	0.003
No	89	1.00
External source of food
Yes	69	0.49 (0.24;0.97)	0.039	0.49 (0.19;1.27)	0.143
No	65	1.00
Alcoholism
Yes	111	2.62 (0.95;7.19)	0.055	2.68 (0.72;9.99)	0.141
No	22	1.00
Disability (physical, hearing or vision)
Yes	34	2.20 (0.99;4.91)	0.050	2.38 (0.77;7.33)	0.130
No	97	1.00
Schooling
Elementary/high school/higher education	111	0.24 (0.09;0.66)	< 0.001	0.55 (0.12;2.52)	0.446
Illiterate	23	1.00
Long-term medication
Yes	28	2.20 (0.94;5.19)	0.065	1.31 (0.41;4.13)	0.650
No	102	1.00
Time of deprivation of liberty in the prison (in years)
> 2	72	2.73 (1.34;5.58)	0.005	0.85 (0.31;2.35)	0.756
≤ 2	59	1.00
Working serving meals
Yes	18	0.37 (0.12;1.11)	0.067	0.91 (0.07;11.74)	0.943
No	120	1.00
Undertaking physical exertion
Yes	46	0.56 (0.27;1.16)	0.118	0.92 (0.32;2.72)	0.892
No	88	1.00

[1] Correspondence:
Leonardo José Alves de Freitas.
e-mail:
leonardojoseph2@hotmail.com

Brasil

Brasil

Investigación de un brote de enfermedad compatible con escorbuto en una penitenciaría masculina en el estado de Ceará, Brasil, 2019-2020: un estudio de casos y controles

RESUMEN

Objetivo:

Métodos:

Resultados:

Conclusión: