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Study of vero cells/PLGA interaction after surface modification by oxygen plasma

The application of bioreabsorbable polymers as support for cells culture is an alternative method to treat lesions and loss of tissues. The surface modifications of these polymers by plasma is an effective and economical technique to make it more hydrophilic. The aim of this work was to study the interactions between Vero cells and PLGA supports previously treated by oxygen plasma, to increase the surface hydrofilicity. The samples were characterized by contact angle, MEV and citochemical analysis. The plasma treatment increased the hydrofilicity, improving the adhesion and cell proliferation, in comparison with the membranes without treatment.

PLGA; plasma; vero cells


Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiro, em cooperação com a Associação Brasileira do Hidrogênio, ABH2 Av. Moniz Aragão, 207, 21941-594, Rio de Janeiro, RJ, Brasil, Tel: +55 (21) 3938-8791 - Rio de Janeiro - RJ - Brazil
E-mail: revmateria@gmail.com