Along the last five years we have treated 112 cases of toxoplasmosis. The majority of them had abortion or corioretinitis; a few had meningo-encephalities, miocarditis or other forms: 8% o f the patients had two anatomoclinical pictures at the same time. The patients received pyrimethamine, sulphametopyrazine, or spiromycine on alternating periods for several months. A Sabin and Feldman test was repeated every three months. The target was obtaining negative serology, th is was accomplished on the majority of the cases. From the clinical stand point cure was supported by disapearance of inflamatory findings on the fundus, disappearing of adenopathy or other signs, as for the achievement of normal pregnancies with normal children in women with repeated abortion. Taking into account the serious secuelae that we have seen on children from mothers with toxoplasmosis, we prefer to treat the women before new pregnancies.