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Development of a word accentuation test for predicting cognitive performance in Portuguese-speaking populations

Desenvolvimento de um teste de acentuação de palavras em português para predição de desempenho cognitivo

ABSTRACT

The Word Accentuation Test (WAT) has been used to predict premorbid intelligence and cognitive performance in Spanish-speaking populations. It requires participants to read a list of words without the accent marks that indicate the stressed syllable.

Objective:

As Portuguese pronunciation is also strongly based on accent marks, our aim was to develop a Brazilian version of the WAT.

Methods:

An initial pool of 60 items was constructed and a final version of 40 items (named WAT-Br) was derived by item response theory. A sample of 206 older adults underwent the WAT-Br and a standardized neuropsychological battery. Independent ratings were performed by two observers in 58 random participants.

Results:

The items showed moderate to high discrimination (α between 0.93 and 25.04) and spanned a wide range of difficulty (β between −2.07 and 1.40). The WAT-Br was shown to have an excellent internal consistency (Kuder-Richardson Formula 20 = 0.95) and inter-rater reliability (intraclass correlation coefficient = 0.92). It accounted for 61% of the variance in global cognitive performance.

Conclusion:

A version of the WAT for Portuguese-speaking populations was developed and proved to be a valuable tool for estimating cognitive performance.

Keywords:
Neuropsychological tests; intelligence; elderly

RESUMO

O Teste de Acentuação de Palavras (TAP) tem sido utilizado para predizer inteligência pré-mórbida e desempenho cognitivo em populações de língua espanhola. Requer que os sujeitos leiam uma lista de palavras sem os sinais gráficos de acentuação que indicam a sílaba tônica.

Objetivo:

Como a pronúncia da língua portuguesa também é fortemente baseada em acentos gráficos, nosso objetivo foi desenvolver uma versão brasileira do TAP.

Métodos:

Um conjunto inicial de 60 itens foi construído e uma versão final de 40 itens (denominada TAP-Br) foi derivada por teoria da resposta ao item. Uma amostra de 206 idosos foi submetida ao TAP-Br e a uma bateria neuropsicológica padronizada. Registros de pontuação independentes foram realizados por dois observadores em uma subamostra de 58 participantes aleatórios.

Resultados:

Os itens apresentaram moderada a alta discriminação (α entre 0,93 e 25,04) e abrangeram uma ampla gama de dificuldades (β entre −2,07 e 1,40). O TAP-Br apresentou excelente consistência interna (Fórmula de Kuder-Richardson 20 = 0,95) e confiabilidade inter-examinador (Coeficiente de Correlação Intraclasse = 0,92). O escore do TAP-Br explicou 61% da variância do desempenho cognitivo global.

Conclusão:

Uma versão do TAP para as populações de língua portuguesa foi desenvolvida e mostrou-se uma ferramenta útil para estimar desempenho cognitivo.

Palavras-chave:
Testes neuropsicológicos; inteligência; idosos

When cognitive decline is suspected, a previous neuropsychological assessment that could serve as a criterion for comparison is rarely available. Thus, one of the great challenges faced in this field is the attempt to estimate premorbid intelligence, a benchmark against which current neuropsychological functioning is compared in order to establish the existence and degree of cognitive decline11. Lezak MD, Howieson DB, Bigler ED, Tranel D. Neuropsychological Assessment. 5th ed. New York: Oxford University Press; 2012..

Reading tests comprising irregularly-spelled words are highly correlated with cognitive performance and have proven to be useful in estimating premorbid intelligence22. Nelson HE, McKenna P The use of current reading ability in the assessment of dementia. Br J Soc Clin Psychol. 1975 Sep;14(3):259-67. https://doi.org/10.1111/j.2044-8260.1975.tb00178.x
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. Those tests can be used for adjusting norms, thus helping clinicians to detect cognitive decline by comparing the actual performance with the performance that would be expected33. Del Pino R, Peña J, Ibarretxe-Bilbao N, Schretlen DJ, Ojeda N. Demographically Calibrated Norms for Two Premorbid Intelligence Measures: The Word Accentuation Test and Pseudo-Words Reading Subtest. Front Psychol. 2018 Oct;9:1950. https://doi.org/10.3389/fpsyg.2018.01950
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. Pronunciation of irregular words must be accessed from a lexical store and not by grapheme-phoneme correspondence rules. Lexical functions that rely on implicit memory are less dependent on higher cognitive processes and, therefore, are relatively stable in normal aging and neuropathological conditions44. Bayles KA, Boone DR. The potential of language tasks for identifying senile dementia. J Speech Hear Disord. 1982 May;47(2):210-7. https://doi.org/10.1044/jshd.4702.210
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. Accordingly, it has been shown that patients with dementia can read irregular words even when their meaning can no longer be assessed55. McGurn B, Starr JM, Topfer JA, Pattie A, Whiteman MC, Lemmon HA, et al. Pronunciation of irregular words is preserved in dementia, validating premorbid IQ estimation. Neurology. 2004 Apr;62(7):1 184-6. https://doi.org/10.1212/01.WNL.0000103169.80910.8B
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The first well-structured reading test designed to estimate premorbid intelligence was the National Adult Reading Test (NART), which requires participants to read aloud a list of 50 words with irregular spelling-sound correspondence66. Nelson HE, O’Connell A. Dementia: the estimation of premorbid intelligence levels using the New Adult Reading Test. Cortex. 1978 Jun;14(2):234-44. https://doi.org/10.1016/S0010-9452(78)80049-5
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. The NART, originally developed in England, has been adapted for North American and Canadian English speakers77. Blair JR, Spreen O. Predicting premorbid IQ: A revision of the national adult reading test. Clin Neuropsychol. 1989;3(2):129-36. https://doi.org/10.1080/13854048908403285
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. Versions of the NART have also been successfully validated in other languages such as Italian, French, Japanese, Korean, and Polish88. Colombo L, Brivio C, Benaglio I, Siri S, Capp SF. Alzheimer patients’ ability to read words with irregular stress. Cortex. 2000 Dec;36(5):703-14. https://doi.org/10.1016/S0010-9452(08)70547-1
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,1010. Matsuoka K, Uno M, Kasai K, Koyama K, Kim Y. Estimation of premorbid IQ in individuals with Alzheimer's disease using Japanese ideographic script (Kanji) compound words: Japanese version of National Adult Reading Test. Psychiatry Clin Neurosci. 2006 Jun;60(3):332-9. https://doi.org/10.1111/j.1440-1819.2006.01510.x
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,1111. Yi D, Seo EH, Han JY, Sohn BK, Byun MS, Lee JH, et al. Development of the Korean Adult Reading Test (KART) to estimate premorbid intelligence in dementia patients. PLoS One. 2017 Jul;12(7):e0181523. https://doi.org/10.1371/journal.pone.0181523
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,1212. Karakuła-Juchnowicz H, Stecka M. [Polish Adult Reading Test (PART) - construction of Polish test for estimating the level of premorbid intelligence in schizophrenia]. Psychiatr Pol. 2017 Aug;51(4):673-85. Polsky. https://doi.org/10.12740/PP/OnlineFirst/63207
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Some languages, such as Swedish, Spanish, and Portuguese, are orthographically transparent, meaning that there is almost total correspondence between graphemes and phonemes. In these languages, versions of the NART seem unattainable, because most readers can pronounce previously-unknown words by using phoneme-grapheme correspondence rules. Therefore, in countries with transparent languages, alternative strategies have been designed to create irregularity between grapheme and phoneme1313. Rolstad S, Nordlund A, Gustavsson MH, Eckerstrom C, Klang O, Hansen S, et al. The Swedish National Adult Reading Test (NART-SWE): a test of premorbid IQ. Scand J Psychol. 2008 Dec;49(6):577-82. https://doi.org/10.1111/j.1467-9450.2008.00677.x
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,1414. Alves L, Simões MR, Martins C. The estimation of premorbid intelligence levels among Portuguese speakers: the Irregular Word Reading Test (TeLPI). Arch Clin Neuropsychol. 2012 Jan;27(1):58-68. https://doi.org/10.1093/arclin/acr103
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Del Ser et al.1515. Del Ser T, González-Montalvo JI, Martínez-Espinosa S, Delgado-Villapalos C, Bermejo F. Estimation of premorbid intelligence in Spanish people with the Word Accentuation Test and its application to the diagnosis of dementia. Brain Cogn. 1997 Apr;33(3):343-56. https://doi.org/10.1006/brcg.1997.0877
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designed the Word Accentuation Test (WAT) by using a newly-proposed source of irregularity between grapheme and phoneme. In Spanish, accent marks are an extra symbol added to existing letters to indicate the stressed syllable. However, when the accent mark is not present, the Spanish readers need to have prior knowledge to achieve a correct pronunciation. Using that rationale, the WAT requests participants to read aloud a list of words without the accent marks. The WAT has been demonstrated to have adequate properties in Spain, Argentina, Colombia, and among Spanishspeaking immigrants in the United States1515. Del Ser T, González-Montalvo JI, Martínez-Espinosa S, Delgado-Villapalos C, Bermejo F. Estimation of premorbid intelligence in Spanish people with the Word Accentuation Test and its application to the diagnosis of dementia. Brain Cogn. 1997 Apr;33(3):343-56. https://doi.org/10.1006/brcg.1997.0877
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,1616. Burin DI, Jorge RE, Arizaga RA, Paulsen JS. Estimation of premorbid intelligence: the word accentuation test: Buenos Aires version. J Clin Exp Neuropsychol. 2000 Oct;22(5):677-85. https://doi.org/10.1076/1380-3395(200010)22:5;1-9;FT677
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,1717. Sierra Sanjurjo N, Montañes P, Sierra Matamoros FA, Burin D. Estimating intelligence in Spanish: regression equations with the word accentuation test and demographic variables in Latin America. Appl Neuropsychol Adult. 2015;22(4):252-61. https://doi.org/10.1080/23279095.2014.918543
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,1818. Schrauf RW, Weintraub S, Navarro E. Is adaptation of the word accentuation test of premorbid intelligence necessary for use among older, Spanish-speaking immigrants in the United States? J Int Neuropsychol Soc. 2006 May;12(3):391-9. https://doi.org/10.1017/S1355617706060462
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.

Brazil is a country with 208 million inhabitants in which Portuguese is the only language in daily life1919. Instituto Brasileiro de Geografia e Estatística - IBGE. Projeção da população do Brasil e das Unidades de Federação. 2018 [cited 2018 Dec 20]. Available from: https://www.ibge.gov.br/apps/populacao/projecao
https://www.ibge.gov.br/apps/populacao/p...
. No validated test is available to assess premorbid intelligence in Brazil. Because Portuguese is also a transparent language and its pronunciation is strongly based on accent marks, our aim was to develop a version of the WAT for Portuguese speakers.

In this study, an initial pool of 60 items was selected and a final version of 40 items (named the WAT-Br) was derived by item response theory. Initial validation criteria were obtained by assessing item discrimination, item difficulty, and correlation with neuropsychological tests. In addition, we calculated the internal consistency and assessed the inter-rater reliability of the proposed test.

METHODS

Elaborating the preliminary version of the test

A preliminary study was conducted to establish an initial list of words that were suited for composing the test. The first step consisted of selecting 300 words with graphic accents from Brazilian Portuguese dictionaries. We did not include: 1) words with more than one possible pronunciation (e.g., “equilátero”); 2) words in which the absence of a graphic accent indicates a different meaning or grammatical class (e.g., “denúncia” vs “denuncia”); 3) words borrowed from other languages (foreignisms); 4) technical jargon; and 5) words with a regional bias determining variation of frequency across the country, such as those representing fauna, flora, cuisine, artistic expressions, or proper names.

Subsequently, three of the authors reviewed the initial pool, through an iterative process and successive discussions, to select 60 words. Because difficulty of pronunciation is influenced by word occurrence, we selected words with a variety of frequencies in the Brazilian corpus: 19 with high frequency (> 1/1,000), 26 with intermediate frequency (between 1/1,000 and 1/10,000), and 15 with low frequency (< 1/10,000)2020. Sardinha TB, Moreira Filho JL, Alambert E. Manual do corpus brasileiro. [cited 2018 Dec 20]. Available from: https://www.linguateca.pt/Repositorio/manual_cb.pdf
https://www.linguateca.pt/Repositorio/ma...
. The selection was conducted with the additional goal of ensuring the same proportion of words stressed in the last, penultimate, and antepenultimate syllable (20/20/20).

Participants

We recruited 206 healthy community-dwelling individuals aged 60 years and older from different regions of the city of São Paulo, in southeast Brazil. Recruitment was targeted to obtain a minimum of 30 participants in each preplanned age and schooling strata, as shown in Table 1. The sample size was calculated to suffice for a two-parameter logistic model with a dichotomously-scored test, in which at least 200 respondents are recommended for accurate parameter estimates2121. Thorpe GL, Andrej F. Data analysis using item response theory methodology: an introduction to selected programs and applications. Psychol Faculty Scholarship. 2012 [cited 2018 Dec 20]. Available from: https://digitalcommons.library.umaine.edu/psy_facp
https://digitalcommons.library.umaine.ed...
.

Table 1
Characteristics of the study sample (n = 206).

General exclusion criteria were: suspected cognitive impairment (consistent self-complaint or cognitive decline reported by a close informant), diagnosis of neurological diseases, psychiatric disorders, use of medications with deleterious effects on the central nervous system, severe or decompensated clinical condition, and severe sensory deficit (visual or auditory). Non-native speakers were allowed to participate as long as they had been living in Brazil for at least 10 years and were perfectly fluent in Portuguese.

Three tests were performed for screening major exclusion criteria. Individuals were excluded if they presented with cognitive impairment indicated by a delayed recall < 7 on the Brief Cognitive Screening Battery2222. Nitrini R, Lefèvre BH, Mathias SC, Caramelli P, Carrilho PE, Sauaia N, et al. [Neuropsychological tests of simple application for diagnosing dementia]. Arq Neuropsiquiatr. 1994 Dec;52(4):457-65. Portuguese. https://doi.org/10.1590/S0004-282X1994000400001
https://doi.org/10.1590/S0004-282X199400...
, functional impairment as indicated by a score > 5 on the Functional Activities Questionnaire2323. Pfeffer RI, Kurosaki TT, Harrah CH Jr, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol. 1982 May;37(3):323-9. https://doi.org/10.1093/geronj/37.3.323
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or fulfilled criteria for major depressive disorder as defined by the Patient Health Questionnaire-92424. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. https://doi.org/10.1046/j.1525-1497.2001.016009606.x
https://doi.org/10.1046/j.1525-1497.2001...
. The study was approved by the institutional review board. All the participants signed an informed consent before the research interview.

Assessment

The respondents received the initial list of 60 words in a descending order of frequency observed in the Brazilian corpus. The items were printed on an A4 sheet, (Times New Roman, font size 20). The test was presented to the examinee as follows: Please, read aloud, slowly, the following words. You may not recognize some words, but try reading them anyway. Examiners scored whether or not the participants pronounced the words correctly and one point was assigned for each correctly read word. Individuals who declared being unable to read even simple words were considered to have a score of zero. The list of words, administration instructions, and scoring rules are available in the Appendix APPENDIX Brazilian Version of the Word Accentuation Test (WAT-Br) 1. VOCE 2. CAFE 3. AÇUCAR 4. POLITICA 5. HEROI 6. APOS 7. ALGUEM 8. TAXI 9. POSTER 10. DOSSIE 11. CANAPE 12. FLEXIVEL 13. TALISMA 14. APRAZIVEL 15. IGARAPE 16. DOCIL 17. CONVES 18. MARTIR 19. CANTARO 20. ELOQUENCIA 21. SINCOPE 22. MUNICIPE 23. LUGUBRE 24. LEXICO 25. AMALGAMA 26. MELIFLUO 27. LANGUIDO 28. UNISSONO 29. ATAVICO 30. MARZIPA 31. ANTIQUISSIMO 32. OBOE 33. EXEGETICO 34. ANTITESE 35. CORTEX 36. AQUIFERO 37. LATEX 38. ARQUETIPO 39. EXEQUIVEL 40. HALUX INSTRUÇÕES ‘Agora eu quero que você leia essas palavras em voz alta. Não se preocupe com o significado das palavras. Apenas leia em voz alta.” “Comece por essa palavra (aponte), passe para a debaixo e assim por diante. Quando terminar essa coluna vá para a próxima coluna (aponte).” “Leia sem pressa, uma palavra de cada vez.” REGRAS DE APLICAÇÃO Caso o sujeito comece a ler rápido interrompa e peça que leia mais devagar. Caso comece a ler em tom de voz baixo interrompa e peça que leia mais alto. Caso você não tenha ouvido bem alguma palavra, solicite que a palavra seja repetida. Interrompa o teste após 10 erros sequenciais. É possível permitir que o indivíduo complete a tarefa mesmo após 10 erros sequenciais, desde que se perceba interesse na tentativa e não haja sinais de constrangimento. Não pontue eventuais pronúncias corretas após 10 erros sequenciais. No caso de desistências precipitadas, tente incentivar para que o indivíduo continue. REGRAS DE PONTUAÇÃO Antes de administrar o teste familiarize-se com a pronúncia das palavras. Atente-se aos erros de sílabas tônicas (acentuação), pronúncia do “X” que pode ter som de “cs” (flexível) ou “z” (exequível) e pronúncia do “QU” que pode ter som de “k” (arquétipo) ou “qü” (eloquência). São aceitas pronúncias variantes por coloquialismo, sotaque ou dicção. No Nordeste é comum a palatização das consoantes “D” e “T”, além da abertura das vogais pre-tônicas. No Rio de Janeiro utiliza-se o “S” palatal e o “R” aspirado. Em Minas Gerais as palavras podem ser encurtadas. Em muitas regiões do país permuta-se o som de “E” por “I” (munícipi) e “O” por “U” (léxicu) no final das palavras. Essas variações devem ser aceitas como corretas. No formulário de aplicação, circule “1” se a pronúncia for correta e “0” se a pronúncia for incorreta. Em caso de autocorreção considere a última tentativa. Um ponto é atribuído a cada palavra pronunciada corretamente (total de 0-40). 1. você 0 1 2. café 0 1 3. açúcar 0 1 4. política 0 1 5. herói 0 1 6. após 0 1 7. al guém [g] 0 1 8. táxi [cs] 0 1 9. pôster 0 1 10. dossiê 0 1 11. canapé 0 1 12. flexível [cs] 0 1 13. talismã 0 1 14. aprazível 0 1 15. igarapé 0 1 16. dócil 0 1 17. convés 0 1 18. mártir 0 1 19. cântaro 0 1 20. eloquência [qu] 0 1 21. síncope 0 1 22. munícipe 0 1 23. lúgubre 0 1 24. léxico [cs] 0 1 25. amálgama 0 1 26. melífluo 0 1 27. lânguido [g] 0 1 28. uníssono 0 1 29. atávico 0 1 30. marzipã 0 1 31. antiquíssimo [qu] 0 1 32. oboé 0 1 33. exegético [z] 0 1 34. antítese 0 1 35. córtex [cs] 0 1 36. aquífero [qu] 0 1 37. látex [cs] 0 1 38. arquétipo [k] 0 1 39. exequível [z][qu] 0 1 40. hálux [cs] 0 1 TOTAL:__________ .

For assessing inter-rater reliability, ratings were performed by two observers in 58 random participants. In this subsample, a resident physician remained in the testing room to record the score of the WAT-Br independently.

All participants underwent a 60-minute standardized neuropsychological battery for evaluating memory (Hopkins Verbal Learning Test-Revised2525. Shapiro AM, Benedict RH, Schretlen D, Brandt J. Construct and concurrent validity of the Hopkins Verbal Learning Test-revised. Clin Neuropsychol. 1999 Aug;13(3):348-58. https://doi.org/10.1076/clin.13.3.348.1749
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and the Logical Memory Test of the Wechsler Memory Scale2626. Woodard JL, Axelrod BN. Parsimonious prediction of Wechsler Memory Scale: revised memory indices. Psychol Assess. 1987;7(4):445-9. http://dx.doi.org/10.1037/1040-3590.7.4.445
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), attention (Forward and Backward Digit Span of the Wechsler Adult Intelligence Scale-III2727. Wechsler D. WAIS—III administration and scoring Manual. San Antonio (TX): The Psychological Corporation; 1997. and Color Trails 12828. Williams J, Rickert v, Hogan J, Zolten AJ, Satz P D’Elia F, et al. Childrens color trails. Arch Clin Neuropsychol. 1995 May-Jun;10(3):211-23. https://doi.org/10.1016/0887-6177(94)00041-N
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), language (Semantic Fluency for Animals2929. Rosen W. Verbal fluency in aging and dementia. J Clin Neuropsychol. 1980;2(2):135-46. https://doi.org/10.1080/01688638008403788
https://doi.org/10.1080/0168863800840378...
and 30-item version Boston Naming Test3030. Park LQ, Gross AL, McLaren DG, Pa J, Johnson JK, Mitchell M, et al.; Alzheimer's Disease Neuroimaging Initiative. Confirmatory factor analysis of the ADNI Neuropsychological Battery. Brain Imaging Behav. 2012 Dec;6(4):528-39. https://doi.org/10.1007/s11682-012-9190-3
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), visuospatial functions (Line Orientation of the Repeatable Battery for the Assessment of Neuropsychological Status3131. Randolph C, Tierney MC, Mohr E, Chase TN. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity. J Clin Exp Neuropsychol. 1998 Jun;20(3):310-9. https://doi.org/10.1076/jcen.20.3.310.823
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and CLOX 13232. Royall DR, Cordes JA, Polk M. CLOX: an executive clock drawing task. J Neurol Neurosurg Psychiatry. 1998 May;64(5):588-94. https://doi.org/10.1136/jnnp.64.5.588
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), and executive functions (Color Trails 22828. Williams J, Rickert v, Hogan J, Zolten AJ, Satz P D’Elia F, et al. Childrens color trails. Arch Clin Neuropsychol. 1995 May-Jun;10(3):211-23. https://doi.org/10.1016/0887-6177(94)00041-N
https://doi.org/10.1016/0887-6177(94)000...
and Matrix Reasoning of the Wechsler Abbreviated Scale of Intelligence3333. Ryan JJ, Carruthers CA, Miller LJ, Souheaver GT, Gontkovsky ST, Zehr MD. The WASI matrix reasoning subtest: performance in traumatic brain injury, stroke, and dementia. Int J Neurosci. 2005 Jan;115(1):129-36. https://doi.org/10.1080/00207450490512704
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). A global composite score was derived by averaging z-scores of the primary measures described above.

Statistical analysis

First, we conducted an exploratory factor analysis to test unidimensionality. A principal component analysis was undertaken based on a tetrachoric correlation matrix. A scree plot of the eigenvalues was derived for visual inspection and the number of factors to be retained was guided by Horn's parallel analysis with 100 randomly generated datasets3434. Horn JL. A rationale and test for the number of factors in factor analysis. Psychometrika. 1965 Jun;30(2):179-85. https://doi.org/10.1007/BF02289447
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.

A two-parameter logistic item response theory model was fitted to provide information regarding discrimination (α) and difficulty (β). Items with discrimination values (α) ranging from 0 to 0.64 show poor discrimination, 0.65 to 1.34 moderate discrimination, 1.35 to 1.69 high discrimination, and above 1.70 very high discrimination3535. Baker FB. The basics of item response theory. 2nd ed. Wisconsin: ERIC Clearinghouse on Assessment and Evaluation; 2001.. Item difficulty values (β) typically range between −2 and +2, with higher values indicating a greater amount of latent trait needed to obtain a correct pronunciation.

The initial pool of items was reduced using a strategy that would maximize psychometric properties and efficiency by selecting items with high discrimination and that were targeted to span a wide range of difficulty levels. To reduce possible redundancy, we eliminated items that were measuring the same level of difficulty.

Internal consistency was assessed using the Kuder-Richardson formula 20 (KR-20), with values above 0.70 indicating satisfactory internal consistency3636. Kuder GF, Richardson MW. The theory of the estimation of test reliability. Psychometrika. 1937;2(3):151-60. https://doi.org/10.1007/BF02288391
https://doi.org/10.1007/BF02288391...
. The intraclass correlation coefficient (ICC) was used to assess inter-rater reliability. The ICC was calculated using a one-way random-effects model for absolute agreement. Values between 0.75 and 0.90 were taken as indicative of good inter-rater agreement and those greater than 0.90 indicated excellent agreement3737. Koo TK, Li MY. A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. J Chiropr Med. 2016 Jun;15(2):155-63. https://doi.org/10.1016/j.jcm.2016.02.012
https://doi.org/10.1016/j.jcm.2016.02.01...
.

Because formal education has been widely used for adjusting norms on neuropsychological tests, we investigated whether the WAT-Br would provide independent predictive power in addition to schooling for predicting cognitive performance. Fractional polynomial regression models were used to account for the nonlinear relationship between predictors and cognitive performance. Nonlinear terms were fitted if they explained variability in the cognitive scores significantly better than a simple linear pattern. The adjusted coefficients of determination of the regression models were used to estimate the proportion of the variance on cognitive performance that could be predicted by the WAT-Br and schooling. The Wald test was used in a hierarchical strategy to test significance of the additional predictor.

All statistical analyses were performed using Stata for Windows, version 14.1 (StataCorp, College Station, TX). The level of statistical significance was set at.05 in two-tailed tests.

RESULTS

Our sample consisted of 206 cognitively unimpaired Brazilians with ages varying from 60 to 98 years (mean 73.6 years; SD = 7.6), representing several levels of formal education (mean 8.0 years; SD = 5.2). Fifteen participants (7.3%) were born in other countries. The immigrants had similar schooling (7.4 vs 8.0; p = 0.666) and a similar performance on the WAT-Br (23.3 vs 23.2; p = 0.968) when compared with native speakers. The characteristics of the sample are shown in Table 1.

The first factor of the 60-item principal component analysis showed an eigenvalue of 32.4 and explained 53.9% of the variance. The second component was substantially smaller, accounting for only 3.4% of the variance. Only the first eigenvalue was greater than the corresponding average in parallel analysis, thus confirming the one-factor structure.

Only one item was excluded for showing poor discrimination (“solideu”; α = 0.63). Significant redundancy was detected for items with difficulty (β) between −1 and 0. Therefore, the 19 items with the lowest discrimination parameters in this difficulty level were eliminated.

The final scale, the WAT-Br, comprised 40 words: 12 with the stress on the last syllable, 13 with stress on the penultimate, and 15 with the stress on the antepenultimate syllable. Items showed moderate-to-high discrimination (α ranging from 0.93 to 25.04) and spanned a wide range of difficulty (β between −2.07 and 1.40; Table 2).

Table 2
Final version of the Brazilian Word Accentuation Test (WAT-Br) with parameter estimates for a two-parameter logistic model.

Overall KR-20 for the 40 items was 0.95, indicating high internal consistency. The ICC between two independent raters was 0.92 (95%CI 0.86 to 0.95), indicating excellent interrater agreement.

Scores of the WAT-Br varied from 0 to 40, with a mean of 23.2 (± 9.5). We observed a normal distribution and only 1.4% of the sample obtained the maximum score, suggesting that the ceiling effect was not a significant problem. The WAT-Br scores did not vary across age and sex strata, but were significantly associated with education and race (Table 1). When adjusted for education, differences between races did not maintain significance and, in a stepwise backward model, the only demographic characteristic associated with the WAT-Br scores was education (β = 1.34; p < 0.001)

A linear relationship was found between the WAT-Br and the global composite score of the neuropsychological battery (Figure), with a Pearson's correlation coefficient of 0.78 and a coefficient of determination (R2) of 0.61, which means that the WAT-Br predicted 61% of the variance in global cognitive performance.

Figure
Scatter plot showing a linear relationship between the WAT-Br and the global composite z-score.

In comparison with schooling, the WAT-Br provided equal or superior prediction of cognitive performance for all neuropsychological scores (Table 3). The addition of the schooling to a model already containing the WAT-Br improved the explained variance modestly for a few neuropsychological measures. On the other hand, the prediction of all neuropsychological measures was significantly improved by adding the WAT-Br to models already containing schooling.

Table 3
Hierarchical strategy to test significance of adding the WAT-Br to a model already containing schooling.

DISCUSSION

In this report we present the development of the Brazilian Word Accentuation Test (WAT-Br) and provide a preliminary investigation of its psychometric properties. From an initial poll of 60 items, we derived a final version with 40 items that was evaluated.

The WAT-Br showed high internal consistency (KR-20 = 0.95). This finding is in line with the versions of the WAT for Spanish-speaking populations that showed values varying from 0.91 to 0.951515. Del Ser T, González-Montalvo JI, Martínez-Espinosa S, Delgado-Villapalos C, Bermejo F. Estimation of premorbid intelligence in Spanish people with the Word Accentuation Test and its application to the diagnosis of dementia. Brain Cogn. 1997 Apr;33(3):343-56. https://doi.org/10.1006/brcg.1997.0877
https://doi.org/10.1006/brcg.1997.0877...
1717. Sierra Sanjurjo N, Montañes P, Sierra Matamoros FA, Burin D. Estimating intelligence in Spanish: regression equations with the word accentuation test and demographic variables in Latin America. Appl Neuropsychol Adult. 2015;22(4):252-61. https://doi.org/10.1080/23279095.2014.918543
https://doi.org/10.1080/23279095.2014.91...
. In addition, an excellent inter-rater agreement was found in our study (ICC = 0.92), aligned with the value found in Spain (ICC = 0.93) by Del Ser et al.1515. Del Ser T, González-Montalvo JI, Martínez-Espinosa S, Delgado-Villapalos C, Bermejo F. Estimation of premorbid intelligence in Spanish people with the Word Accentuation Test and its application to the diagnosis of dementia. Brain Cogn. 1997 Apr;33(3):343-56. https://doi.org/10.1006/brcg.1997.0877
https://doi.org/10.1006/brcg.1997.0877...
Finally, the WAT-Br accounted for 61% of the variance observed in the global composite score for current cognitive performance, a value that is in the range of those found by studies that used the WAT to predict the WAIS full-scale IQ in Spanish-speaking samples1717. Sierra Sanjurjo N, Montañes P, Sierra Matamoros FA, Burin D. Estimating intelligence in Spanish: regression equations with the word accentuation test and demographic variables in Latin America. Appl Neuropsychol Adult. 2015;22(4):252-61. https://doi.org/10.1080/23279095.2014.918543
https://doi.org/10.1080/23279095.2014.91...
.

This is the first study to show that the ability of reading Portuguese words without accent marks is a good indicator of lexical knowledge and that this task may be an efficient way of estimating cognitive performance in Portuguesespeaking adults. This finding is of paramount importance for most Portuguese-speaking countries, where social inequality remains a relevant problem. In those countries, with heterogeneous quality of education, schooling may not be the best indicator of premorbid cognitive performance.

Our study included a heterogeneous sample. A significant proportion of the participants (40.8%) were not white and a wide range of schooling levels were represented. Nineteen unschooled individuals were included and 68.4% of them were able to read at least one word, thus revealing that the WAT-Br can discriminate performance even in populations with very low levels of schooling or no schooling at all. We also included individuals born in other countries. Brazil received many European and Japanese immigrants during World War II. Therefore, the inclusion of non-native speakers was important to improve the external validity of the study.

An irregular word reading test, the TeLPI, was developed in Portugal using the very few grapheme-phoneme irregularities encountered in Portuguese1313. Rolstad S, Nordlund A, Gustavsson MH, Eckerstrom C, Klang O, Hansen S, et al. The Swedish National Adult Reading Test (NART-SWE): a test of premorbid IQ. Scand J Psychol. 2008 Dec;49(6):577-82. https://doi.org/10.1111/j.1467-9450.2008.00677.x
https://doi.org/10.1111/j.1467-9450.2008...
, namely the pronunciation of the intervocalic “x” or the syllables “que/qui/gue/gui”, that can have more than one pronunciation3838. Alves L, Martins C. Simões MR. Premorbid Intelligence Evaluation: development of the experimental version of the Irregular Words Reading Test (TeLPI) for Portuguese Population. Psychologia. 2010;53:299-312. https://doi.org/10.14195/1647-8606_53_14
https://doi.org/10.14195/1647-8606_53_14...
. The TeLPI was able to predict only 53% of the variance of the WAIS full-scale IQ1414. Alves L, Simões MR, Martins C. The estimation of premorbid intelligence levels among Portuguese speakers: the Irregular Word Reading Test (TeLPI). Arch Clin Neuropsychol. 2012 Jan;27(1):58-68. https://doi.org/10.1093/arclin/acr103
https://doi.org/10.1093/arclin/acr103...
. In contrast, in Spanish-speaking populations, the WAT predicted between 59% and 70% of the variance in the WAIS full-scale IQ scores1515. Del Ser T, González-Montalvo JI, Martínez-Espinosa S, Delgado-Villapalos C, Bermejo F. Estimation of premorbid intelligence in Spanish people with the Word Accentuation Test and its application to the diagnosis of dementia. Brain Cogn. 1997 Apr;33(3):343-56. https://doi.org/10.1006/brcg.1997.0877
https://doi.org/10.1006/brcg.1997.0877...
,1717. Sierra Sanjurjo N, Montañes P, Sierra Matamoros FA, Burin D. Estimating intelligence in Spanish: regression equations with the word accentuation test and demographic variables in Latin America. Appl Neuropsychol Adult. 2015;22(4):252-61. https://doi.org/10.1080/23279095.2014.918543
https://doi.org/10.1080/23279095.2014.91...
. These findings suggest that exploring the few grapheme-phoneme irregularities encountered in Portuguese may be a limited strategy. Future studies using the WAT to predict the WAIS full-scale IQ in Portuguesespeaking populations will provide more adequate parameters of comparison between these two assessment strategies.

Although the focus of our test was the ability to read words without the accent marks, items with additional elements of irregularity were not excluded. Indeed, 10 of the 40 words of the final list contained an intervocalic “x” or the syllables “que/qui/gue/gui”. Therefore, the WAT-Br is not a pure test in its linguistic mechanism of irregularity. As can be seen in Table 2, words with additional irregularities are among the most difficult and were important to avoid a ceiling effect. A concern could be raised about the presence of more than one irregularity mechanism increasing the variance. However, that concern was not confirmed, once the test showed an excellent internal consistency.

This research has some limitations that should be noted. Firstly, although a sample with 206 participants was deemed sufficient for a two-parameter logistic model, a larger sample would have provided more accurate parameter estimates. Secondly, although the sample was diverse and represented a wide range of schooling levels, this was a single-center study. Further research with samples from different regions of the country is needed to validate our findings. Thirdly, only a few items had a difficulty parameter (β) above 1, raising the concern that the WAT-Br may be a limited tool for estimating cognitive performance in persons with high levels of the latent trait. In this study, we found a linear relationship between the WAT-Br and cognitive performance without a plateau at higher levels. However, because the ceiling effect has been a common phenomenon among tests of irregular words, this concern should be examined in highly-educated individuals.

In conclusion, a version of the WAT for Portuguesespeaking populations has been developed and proved to be a valid tool for estimating cognitive performance. Future studies should evaluate the WAT-Br as a predictor of intelligence and evaluate its stability in patients with cognitive impairment.

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APPENDIX Brazilian Version of the Word Accentuation Test (WAT-Br)

1. VOCE
2. CAFE
3. AÇUCAR
4. POLITICA
5. HEROI
6. APOS
7. ALGUEM
8. TAXI
9. POSTER
10. DOSSIE
11. CANAPE
12. FLEXIVEL
13. TALISMA
14. APRAZIVEL
15. IGARAPE
16. DOCIL
17. CONVES
18. MARTIR
19. CANTARO
20. ELOQUENCIA
21. SINCOPE
22. MUNICIPE
23. LUGUBRE
24. LEXICO
25. AMALGAMA
26. MELIFLUO
27. LANGUIDO
28. UNISSONO
29. ATAVICO
30. MARZIPA
31. ANTIQUISSIMO
32. OBOE
33. EXEGETICO
34. ANTITESE
35. CORTEX
36. AQUIFERO
37. LATEX
38. ARQUETIPO
39. EXEQUIVEL
40. HALUX
INSTRUÇÕES
  • ‘Agora eu quero que você leia essas palavras em voz alta. Não se preocupe com o significado das palavras. Apenas leia em voz alta.”

  • “Comece por essa palavra (aponte), passe para a debaixo e assim por diante. Quando terminar essa coluna vá para a próxima coluna (aponte).”

  • “Leia sem pressa, uma palavra de cada vez.”

REGRAS DE APLICAÇÃO
  • Caso o sujeito comece a ler rápido interrompa e peça que leia mais devagar.

  • Caso comece a ler em tom de voz baixo interrompa e peça que leia mais alto.

  • Caso você não tenha ouvido bem alguma palavra, solicite que a palavra seja repetida.

  • Interrompa o teste após 10 erros sequenciais. É possível permitir que o indivíduo complete a tarefa mesmo após 10 erros sequenciais, desde que se perceba interesse na tentativa e não haja sinais de constrangimento. Não pontue eventuais pronúncias corretas após 10 erros sequenciais.

  • No caso de desistências precipitadas, tente incentivar para que o indivíduo continue.

REGRAS DE PONTUAÇÃO
  • Antes de administrar o teste familiarize-se com a pronúncia das palavras. Atente-se aos erros de sílabas tônicas (acentuação), pronúncia do “X” que pode ter som de “cs” (flexível) ou “z” (exequível) e pronúncia do “QU” que pode ter som de “k” (arquétipo) ou “qü” (eloquência).

  • São aceitas pronúncias variantes por coloquialismo, sotaque ou dicção. No Nordeste é comum a palatização das consoantes “D” e “T”, além da abertura das vogais pre-tônicas. No Rio de Janeiro utiliza-se o “S” palatal e o “R” aspirado. Em Minas Gerais as palavras podem ser encurtadas. Em muitas regiões do país permuta-se o som de “E” por “I” (munícipi) e “O” por “U” (léxicu) no final das palavras. Essas variações devem ser aceitas como corretas.

  • No formulário de aplicação, circule “1” se a pronúncia for correta e “0” se a pronúncia for incorreta.

  • Em caso de autocorreção considere a última tentativa.

  • Um ponto é atribuído a cada palavra pronunciada corretamente (total de 0-40).

1. vo 0 1
2. ca 0 1
3. açúcar 0 1
4. potica 0 1
5. herói 0 1
6. após 0 1
7. al guém [g] 0 1
8. xi [cs] 0 1
9. ster 0 1
10. dossiê 0 1
11. cana 0 1
12. flevel [cs] 0 1
13. talis 0 1
14. apravel 0 1
15. igara 0 1
16. cil 0 1
17. convés 0 1
18. rtir 0 1
19. ntaro 0 1
20. eloquência [qu] 0 1
21. ncope 0 1
22. mucipe 0 1
23. gubre 0 1
24. xico [cs] 0 1
25. algama 0 1
26. mefluo 0 1
27. nguido [g] 0 1
28. uníssono 0 1
29. avico 0 1
30. marzi 0 1
31. antiquíssimo [qu] 0 1
32. oboé 0 1
33. exetico [z] 0 1
34. antese 0 1
35. rtex [cs] 0 1
36. aquífero [qu] 0 1
37. tex [cs] 0 1
38. arquétipo [k] 0 1
39. exequível [z][qu] 0 1
40. lux [cs] 0 1
TOTAL:__________

Publication Dates

  • Publication in this collection
    05 Sept 2019
  • Date of issue
    Aug 2019

History

  • Received
    20 Dec 2018
  • Reviewed
    18 Mar 2019
  • Accepted
    24 Apr 2019
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