Gravidez após transplante hepático

Coelho, Júlio Cezar Uili; Wiederkehr, Júlio Cesar; Parolin, Mônica Beatriz; Balbi, Elizabeh; Tereza, Luiz A.; Nassif, Aissar Eduardo

doi:10.1590/S0100-69911998000600017

Resumo

The objective of the present study is to report a sucessful pregnancy in a 28 year-old female who underwent an orthotopic liver transplantation two years ago due to type I auto immune he patitis. Patient was taking cyclosporin, prednisone and azathioprine for maintenance immunossupression and had good graft function during all the pregnancy. The liver function tests were normal during the pregnancy. Fetal growth was monitored by ultrasonographic examination and showed normal development. At the end of the third trimester, she was subjected to a cesarean bearing a healthy girl weighting 2,320 kg. She was discharged with normal liver functions tests and no complications.

Pregnancy; Liver transplantation; Hepatitis

RELATOS DE CASOS

Gravidez após transplante hepático

Sucessful pregnancy after liver transplantation

Júlio Cezar Uili Coelho, TCBC-PR^I; Júlio Cesar Wiederkehr, TCBC-PR^II; Mônica Beatriz Parolin^III; Elizabeh Balbi^III; Luiz A. Tereza^IV; Aissar Eduardo Nassif^V

^IProfessor Titular e Chefe da Disciplina de Cirurgia do Aparellho Digestivo

^IIPo rofessor Adjunto da Disciplina de Cirurgia do Aparelho Digestivo

^IIIMédica Hepatologista do Serviço de Transplante Hepático

^IVProfessor Adjunto do Departamento de Tocoginecologia

^VAcadêmico de Medicina do 6 anos

^{Endereço para correspondência} Endereço para correspondência: Dr. Júlio Cezar Uili Coelhoo Viana, 11 Rua Bento Viana, 1140/2202 80240-110 - Curitiba - PR

ABSTRACT

The objective of the present study is to report a sucessful pregnancy in a 28 year-old female who underwent an orthotopic liver transplantation two years ago due to type I auto immune he patitis. Patient was taking cyclosporin, prednisone and azathioprine for maintenance immunossupression and had good graft function during all the pregnancy. The liver function tests were normal during the pregnancy. Fetal growth was monitored by ultrasonographic examination and showed normal development. At the end of the third trimester, she was subjected to a cesarean bearing a healthy girl weighting 2,320 kg. She was discharged with normal liver functions tests and no complications.

Key words: Pregnancy; Liver transplantation; Hepatitis.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Recebido em 5/5/98

Aceito para publicação em 2/8/98

Trabalho realizado nos Serviços de Transplane Hepático de Tocoginecologia do Hospital de Clínicas da Universidade Federal do Paraná.

Referências bibliográficas

1. Albengres H, LeLouet H, Tillement JP. Imunossupressive drugs and pregnancy: experimental and clinical data. Transplant Proc 1997; 29:2.4612.466.
2. Boisriveaud CH, Pons V, Lefrançois N, et al. Transplant and fetus: how do they coexist in the maternal mind. Transplant Proc 1997; 29:2.475-6.
3. Scantlebury V, Gordon R, Tzakis A, et al. Childbearing after liver transplantation. Transplantation 1990;49:317-21.
4. Radomski JS, Moritz MJ, Munoz SJ. National pregnancy registry: analysis of pregnancy outcomes in females liver transplant recipients. Liver Transplant Surg 1997;1:281-4.
5. Pruvot FR, Declerk N, Valat-Rigot AS, et al. Pregnancy after liver transplantation: focusing on risks to the mother. Transplantion Proc 1997;29:2.470-1.

Endereço para correspondência:

Dr. Júlio Cezar Uili Coelhoo Viana, 11

Rua Bento Viana, 1140/2202

80240-110 - Curitiba - PR

Datas de Publicação

Publicação nesta coleção
31 Maio 2010
Data do Fascículo
Dez 1998

Histórico

Aceito
02 Ago 1998
Recebido
05 Maio 1998

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Albengres H, LeLouet H, Tillement JP. Imunossupressive drugs and pregnancy: experimental and clinical data. Transplant Proc 1997; 29:2.4612.466.

[2] 2. Boisriveaud CH, Pons V, Lefrançois N, et al. Transplant and fetus: how do they coexist in the maternal mind. Transplant Proc 1997; 29:2.475-6.

[3] 3. Scantlebury V, Gordon R, Tzakis A, et al. Childbearing after liver transplantation. Transplantation 1990;49:317-21.

[4] 4. Radomski JS, Moritz MJ, Munoz SJ. National pregnancy registry: analysis of pregnancy outcomes in females liver transplant recipients. Liver Transplant Surg 1997;1:281-4.

[5] 5. Pruvot FR, Declerk N, Valat-Rigot AS, et al. Pregnancy after liver transplantation: focusing on risks to the mother. Transplantion Proc 1997;29:2.470-1.