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Oral management of a patient with cemento-osseous dysplasia: a case report

Manejo oral de paciente com displasia cemento-óssea: relato de caso

ABSTRACT

Florid cemento-osseous dysplasia is a subtype of fibrous-osseous lesion that commonly appears in the jaws of middle-aged black women. Clinically, the florid cemento-osseous dysplasia is asymptomatic. The radiographic aspect shows a radiolucent area with several masses of radiopaque structures, typically found in the toothbearing areas. Usually, the diagnosis is made during routine radiographic examination. The treatment is required when infection occurs due to exposure of the lesion in the oral cavity. In these severe cases, pain and facial deformity may be present. Commitment oral hygiene and routine dental visits for check-up are recommended for individuals affected. The objective of this study was to present a clinical case of a 24-year-old white woman with florid cemento-osseous dysplasia, who had been under surveillance for 13 years. Some changes in the radiographic pattern were observed as the orthodontic treatment was carried out in a private service. No tooth extraction was performed. This change is expected because florid cemento-osseous dysplasia has different radiographic aspects that correspond to the different developmental stages of the lesion. It is suggested, however, that the presence of florid cemento-osseous dysplasia did not preclude the success of the orthodontic treatment.

Indexing terms
Oral pathology; Orthodontics; Radiography

RESUMO

A displasia cemento-óssea florida é um subtipo de lesão fibro-óssea que geralmente aparece nos ossos gnáticos de mulheres negras de meia idade. Clinicamente a displasia cemento-óssea florida é assintomática. Os aspectos radiográficos mostram uma área radiolucente com várias massas de estruturas radiopacas, tipicamente encontradas próximas às raízes dos dentes. O tratamento é requerido quando ocorre infecção devido à exposição da lesão na cavidade oral. Em casos mais severos, dor e deformidade podem estar presentes. Concomitante a higiene oral, visitas de rotina ao dentista são recomendadas ao indivíduo afetado. O objetivo deste estudo foi apresentar o caso clínico de uma mulher de 24 anos de idade, cor da pele branca com diagnóstico de displasia cemento-óssea florida com acompanhamento de 13 anos. Algumas alterações no padrão radiográfico foram observadas, como a mineralização progressiva da lesão. Tratamento ortodôntico foi realizado em um serviço privado. Não foi realizado exodontia. Esta alteração era esperada, pois a displasia cemento-óssea florida tem diferentes estágios de desenvolvimento. É sugerido, portanto, que a presença da displasia cemento-óssea florida não impediu o sucesso do tratamento ortodôntico.

Termos de indexação
Patologia bucal; Ortodontia; Radiografia

INTRODUCTION

Fibro-osseous lesions are conditions that may affect the bones of the maxillofacial region. In general, the normal bone is replaced by cellular fibroblastic tissue containing calcified structures (osseous or cementum-like structures) [11 Waldron CA. Fibro-osseous lesions of the jaw. J Oral Maxillofac Surg. 1985;43(4):249-62.

2 Mccarthy EF. Fibro-osseous lesions of the maxillofacial bones. Head Neck Pathol. 2013;7(1):5-10. http://dx.doi.org/10.1007/s12105-013-0430-7
https://doi.org/10.1007/s12105-013-0430-...
-33 Fenerty S, Shaw W, Verma R, Syed AB, Kuklani R, Yang J, et al. Florid cemento-osseous dysplasia: review of an uncommon fibro-osseous lesion of the jaw with important clinical implications. Skeletal Radiol. 2017;46(5):581-90. http://dx. doi.org/10.1007/s00256-017-2590-0
https://doi.org/10.1007/s00256-017-2590-...
]. According to the World Health Organization, the ossifying fibroma, familial gigantiform cementoma, fibrous dysplasia and cemento-osseous dysplasia have been included in the group of fibro-osseous lesions [44 El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of head and neck tumours. 4th ed. Lyon: IARC Press; 2017.].

Cemento-osseous dysplasias (CODs) are reported as the most frequent fibro-osseous lesion in clinical practice. According to the place of manifestation and the extent, CODs may present three subtypes: periapical cemento-osseous dysplasia, focal cemento-osseous dysplasia and florid cemento-osseous dysplasia [44 El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of head and neck tumours. 4th ed. Lyon: IARC Press; 2017.]. Florid cemento-osseous dysplasia (FCOD) is a more extensive form, occurring bilaterally in the mandible. The radiographic aspect of FCOD is characterized by multiple radiopaque areas with an aspect of lobulated masses [55 de Noronha Santos Netto J, Machado Cerri J, Miranda AM, Pires FR. Benign fibroosseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(5):56-65. http://dx.doi.org/10.1016/j.oooo.2012.05.022
https://doi.org/10.1016/j.oooo.2012.05.0...
,66 Alsufyani NA, Lam EWN. Osseous (cemento-osseous) dysplasia of the jaws: clinical and radiographic analysis. J Can Dent Assoc. 2011;77(70b):1-8.]. If exposed to oral cavity, the acellular sclerotic bone can be infected, resulting in osteomyelitis frame [77 Köse TE, Köse OD, Karabas HC, Erdem TL, Özcan I. Findings of florid cemento-osseous dysplasia: a report of three cases. J Oral Maxillofac Res. 2013;4(4):1-6. http://dx.doi.org/10.5037/jomr.2013.4404
https://doi.org/10.5037/jomr.2013.4404...
,88 Cavalcante MB, de Oliveira Lima AL, Júnior MA, Santos MB. Florid cemento-osseous dysplasia simultaneous the chronic suppurative osteomyelitis in mandible. J Craniofac Surg. 2016;27(8):2173-6. http://dx.doi.org/10.1097/SCS.0000000000003095
https://doi.org/10.1097/SCS.000000000000...
].

All subtypes of COD have similar histopathological aspects and the diagnosis of FCOD is based on the clinical and radiographic features [11 Waldron CA. Fibro-osseous lesions of the jaw. J Oral Maxillofac Surg. 1985;43(4):249-62.]. Due to the risk of infection, osteomyelitis and bone sequestrum formation, biopsy should be performed only in cases in which the radiolografic and clinical findings are insufficient for a diagnosis [77 Köse TE, Köse OD, Karabas HC, Erdem TL, Özcan I. Findings of florid cemento-osseous dysplasia: a report of three cases. J Oral Maxillofac Res. 2013;4(4):1-6. http://dx.doi.org/10.5037/jomr.2013.4404
https://doi.org/10.5037/jomr.2013.4404...
,99 Doi R, Fujii N, Okamoto A Okamoto H, Kidani K, Takubo K, et al. Florid osseous dysplasia: a case report and literature review. J Oral Maxillofac Surg Med Pathol. 2014;26:535-9. http://dx.doi.org/10.1016/j.ajoms.2013.06.001
https://doi.org/10.1016/j.ajoms.2013.06....
]. Patients should be followed-up for observation of clinical and radiographic alterations [1010 Senia ES, Sarao MS. Periapical cemento-osseous dysplasia: a case report with twelve-year follow-up and review of literature. Int Endod J. 2015;48(11):1086-99. http://dx.doi.org/10.1111/iej.12417
https://doi.org/10.1111/iej.12417...
,1111 Pereira DL, Pires FR, Lopes MA, Carlos R, Wright JM, Patel P, et al. Clinical, demographic, and radiographic analysis of 82 patients affected by florid osseous dysplasia: an international collaborative study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(2):250-7. http://dx.doi.org/10.1016/j.0000.2016.04.013
https://doi.org/10.1016/j.0000.2016.04.0...
]. Referral of patients with FCOD to orthodontics and other allied specialties of dentistry should be done carefully [1212 Minhas G, Hodge T, Gill, DS. Orthodontic treatment and cemento-osseous dysplasia: a case report. J Orthod. 2008;35(2):90-5. http://dx.doi.org/10.1179/146531207225022500
https://doi.org/10.1179/1465312072250225...
,1313 Sethusa MP, Khan MI. The orthodontic management of a patient presenting with cemento-osseous dysplasia. SADJ. 2009;64(3):120-4.]. Taking into account the afore-mentioned statements, the aim of this study was to present a case of a 24-year-old woman with FCOD, who had been under surveillance for 13 years.

CASE REPORT

A 24-year-old white female was referred, in 2004, to the Department of Oral Surgery and Pathology at the Dental School of the Universidade Federal de Minas Gerais, for evaluation of a painless and hardened growth in the left posterior mandible. The medical and familiar history of the patient was non-contributory. The extra-oral examination revealed no significant finding. Intra-oral assessment showed the presence of a slight increase in the volume of the buccal alveolar bone in the area of the mandibular left pre-molars. Gingiva and oral mucosa showed no signs of inflammation. Filled and missing teeth were not observed.

The panoramic radiograph showed a radiopaque mass with a lobular pattern in a well-defined, round and radiolucent area around the apex of the mandibular left second pre-molar. A radiopaque area was also observed in the alveolar bone between the mandibular right first and second pre-molars and between the mandibular right second pre-molar and first molar (figure 1). The periapical radiograph of anterior region of the mandible showed bone changes close to the apex of the mandibular central incisors similar to those of the posterior region (figure 2). The mandibular incisors, the mandibular left and right pre-molars and the mandibular first molar responded positively to pulp vitality tests. Serum calcium, phosphorus, alkaline phosphatase, parathyroid hormone and vitamin D showed normal levels.

Figure 1
Panoramic radiograph in 2004 showing florid cemento-osseous dysplasia affecting mandible.
Figure 2
Periapical radiograph of the mandibular incisors area at early stage.Well-defined radiolucent area with small radiopacity inside.

Due to bone expansion an incisional biopsy was carried out in the area of the mandibular left second pre-molar. This exam showed fragments of benign fibro-osseous tissue with the presence of calcified structures, represented by immature bone tissue with fibrous connective tissue (figure 3). Following the analysis of clinical, radiographic and histopathological features, the diagnosis of FCOD was confirmed.

Figure 3
Histopathological aspect of the lesion.

The patient was placed under periodic surveillance to evaluate possible changes of the lesion (figure 4A). The clinical and radiographic exams, as well as pulp vitality tests of the teeth involved were performed every 2 years. In 2006, the patient manifested discomfort with the spacing between the teeth. Orthodontic treatment was carried out in a private service. No tooth extraction was indicated. The patient was advised to keep a strict regime of oral hygiene with adequate tooth-brushing and flossing as well as routine dental appointments for plaque control. Three years after orthodontic treatment onset, the panoramic radiograph showed a change in the radiographic pattern of the lesion in the left posterior mandible. A round radiopaque mass of calcified tissue was observed in contact with the root of the mandibular left pre-molar, surrounded by a radiolucent area. An increase of the lesion in the anterior mandible was also observed. On the day of orthodontic appliance debonding, panoramic radiograph demonstrated no change in the radiographic aspect in the area of the mandibular left second pre-molar. The lesion in the anterior mandible increased in size, extending from the mandibular right canine to the mandibular left canine. A radiopaque mass surrounded by radiolucent area was observed in this area (figure 4B).

Figure 4
A) Panoramic radiograph in 2006. Patient under surveillance. B) Panoramic radiograph on the day of debonding. Increase of radiopaque areas withinthe lesion.

In 2014, for more detailed examination, cone beam computed tomography (CBCT) was obtained (figures 5). Axial and coronal slice images revealed a hypodense and multifocal lesion with a hyperdense mass close to the mandibular left pre-molars. Expansion, without perforation, was also observed in the buccal and lingual cortical bone. Coronal slices showed an extensive high-density mass close to the mandibular left lateral incisor and the mandibular left canine with discontinuity or absence of the lamina dura of the periodontal ligament space.

Figure 5
A) Axial slice of cone beam computed tomography taken in 2014 showing expansion of the buccal and lingual cortical. B) Superior axial slice showing expansion without perforation of the anterior buccal and lingual cortical bone. C) Coronal slice displaying discontinuity and absence of lamina dura in posterior region. D) Anterior coronal slice. Fibrous cement-osseous dysplasia causing discontinuity or absence of the lamina dura.

During the surveillance, the patient has been encouraged to undergo routine dental appointments and to maintain strict oral hygiene to avoid inflammation that can affect the altered bone. In the last dental visit for check up, only panoramic radiograph was performed. An increased radiopacity was observed in the lesion (figure 6). Written informed consent of the patient was obtained for publication of the case report.

Figure 6
13-year follow-up panoramic radiograph.

DISCUSSION

The etiology of the CODs remains unknown, but it may be associated with hormonal and genetic factors [55 de Noronha Santos Netto J, Machado Cerri J, Miranda AM, Pires FR. Benign fibroosseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(5):56-65. http://dx.doi.org/10.1016/j.oooo.2012.05.022
https://doi.org/10.1016/j.oooo.2012.05.0...
]. FCOD is most commonly observed among middle-aged black women [11 Waldron CA. Fibro-osseous lesions of the jaw. J Oral Maxillofac Surg. 1985;43(4):249-62.,22 Mccarthy EF. Fibro-osseous lesions of the maxillofacial bones. Head Neck Pathol. 2013;7(1):5-10. http://dx.doi.org/10.1007/s12105-013-0430-7
https://doi.org/10.1007/s12105-013-0430-...
,1414 Fernandes DT, Pereira DL, Santos-Silva AR, Vargas PA, Lopes MA. Florid osseous dysplasia associated with multiple simple bone cysts: a patient with 22 years of follow-up. Gen Dent. 2016;64(2):21-5.]. The present case, however, describes a young female caucasian patient. Periapical and focal CODs affect restricted areas of jawbones and are usually asymptomatic. The diagnosis is made with routine radiographs. FCODs affect the mandible in 100% of the cases, while the maxilla is simultaneous involved in approximately 50% [1515 MacDonald DS. Maxillofacial fibro-osseous lesions. Clin Radiol. 2015;70:25-36. http://dx.doi.org/10.1016/j.crad.2014.06.022
https://doi.org/10.1016/j.crad.2014.06.0...
].

There are some cases of FCOD in which the patients report mild and intermittent pain in the affected area, especially after trauma or secondary infection [33 Fenerty S, Shaw W, Verma R, Syed AB, Kuklani R, Yang J, et al. Florid cemento-osseous dysplasia: review of an uncommon fibro-osseous lesion of the jaw with important clinical implications. Skeletal Radiol. 2017;46(5):581-90. http://dx. doi.org/10.1007/s00256-017-2590-0
https://doi.org/10.1007/s00256-017-2590-...
,88 Cavalcante MB, de Oliveira Lima AL, Júnior MA, Santos MB. Florid cemento-osseous dysplasia simultaneous the chronic suppurative osteomyelitis in mandible. J Craniofac Surg. 2016;27(8):2173-6. http://dx.doi.org/10.1097/SCS.0000000000003095
https://doi.org/10.1097/SCS.000000000000...
,99 Doi R, Fujii N, Okamoto A Okamoto H, Kidani K, Takubo K, et al. Florid osseous dysplasia: a case report and literature review. J Oral Maxillofac Surg Med Pathol. 2014;26:535-9. http://dx.doi.org/10.1016/j.ajoms.2013.06.001
https://doi.org/10.1016/j.ajoms.2013.06....
,1616 More CB, Shirolkar R, Adalja C, Tailor MN. Florid cement-osseous dysplasia of maxilla and mandible: a rare clinical case. Braz J Oral Sci. 2012;11(4):513-7. http://dx.doi.org/10.1590/S1677-32252012000400015
https://doi.org/10.1590/S1677-3225201200...
]. In this case report, the patient has been followed up for a long period (thirteen years) and she has reported no symptoms associated with the lesion. Only the swelling was observed. CODs are often limited to the alveolar process, leading to minimal expansion [66 Alsufyani NA, Lam EWN. Osseous (cemento-osseous) dysplasia of the jaws: clinical and radiographic analysis. J Can Dent Assoc. 2011;77(70b):1-8.,1515 MacDonald DS. Maxillofacial fibro-osseous lesions. Clin Radiol. 2015;70:25-36. http://dx.doi.org/10.1016/j.crad.2014.06.022
https://doi.org/10.1016/j.crad.2014.06.0...
]. If cortical expansion with increase of the volume is present, a more in-depth investigation should be performed.

The diagnosis of fibro-osseous lesions is challenging because of the great similarity of features among the lesions of the same group and other bone alterations as Paget’s disease, chronic diffuse osteomyelitis [77 Köse TE, Köse OD, Karabas HC, Erdem TL, Özcan I. Findings of florid cemento-osseous dysplasia: a report of three cases. J Oral Maxillofac Res. 2013;4(4):1-6. http://dx.doi.org/10.5037/jomr.2013.4404
https://doi.org/10.5037/jomr.2013.4404...
,1717 Önder B, Kursun S, Öztas B, Baris E, Erdem E. Florid osseous dysplasia in a middle-aged Turkish woman: a case report. Imaging Sci Dent. 2013;43(3):197-200. http://dx.doi.org/10.5624/isd.2013.43.3.197
https://doi.org/10.5624/isd.2013.43.3.19...
] and inflammatory lesions [1818 Huh JK, Shin SJ. Misdiagnosis of florid cemento-osseous dysplasia leading to unnecessary root canal treatment: a case report. Restor Dent Endod. 2013;38(3):160-6. http://dx.doi.org/10.5395/rde.2013.38.3.160
https://doi.org/10.5395/rde.2013.38.3.16...
]. Osteosarcomas and familial gigantiform cementoma should be also considered in the differential diagnosis. The combination of clinical, radiographic and histological data may contribute significantly to the final diagnosis of CODs. Careful observation of the characteristics of the lesion and a definitive diagnosis avoid unnecessary treatments [1010 Senia ES, Sarao MS. Periapical cemento-osseous dysplasia: a case report with twelve-year follow-up and review of literature. Int Endod J. 2015;48(11):1086-99. http://dx.doi.org/10.1111/iej.12417
https://doi.org/10.1111/iej.12417...
,1818 Huh JK, Shin SJ. Misdiagnosis of florid cemento-osseous dysplasia leading to unnecessary root canal treatment: a case report. Restor Dent Endod. 2013;38(3):160-6. http://dx.doi.org/10.5395/rde.2013.38.3.160
https://doi.org/10.5395/rde.2013.38.3.16...
,1919 Delai D, Bernardi A, Felippe GS, Da Silveira Texeira C, Felippe WT, Santos Felippe MC. Florid cemento-osseous dysplasia: a case of misdiagnosis. J Endod. 2015;41(11):1923-6. http://dx.doi.org/10.1016/j.joen.2015.08.016
https://doi.org/10.1016/j.joen.2015.08.0...
]. In the present case, biopsy and histopathological exam was necessary to confirm the diagnosis of FCOD.

Management of asymptomatic patients requires periodic follow-up for clinical and radiographic evaluations. Another long follow-up of a patient with periapical COD has been reported elsewhere. This patient with a lesion affecting the anterior mandible had been followed-up for 12 years, but no intervention was carried out [1010 Senia ES, Sarao MS. Periapical cemento-osseous dysplasia: a case report with twelve-year follow-up and review of literature. Int Endod J. 2015;48(11):1086-99. http://dx.doi.org/10.1111/iej.12417
https://doi.org/10.1111/iej.12417...
]. The author only stressed the importance of periodic control of the patient with oral prophylaxis and reinforced the relevance of good oral hygiene to prevent periodontal disease and tooth loss. The need for a careful plaque control has been emphasized in the literature [99 Doi R, Fujii N, Okamoto A Okamoto H, Kidani K, Takubo K, et al. Florid osseous dysplasia: a case report and literature review. J Oral Maxillofac Surg Med Pathol. 2014;26:535-9. http://dx.doi.org/10.1016/j.ajoms.2013.06.001
https://doi.org/10.1016/j.ajoms.2013.06....
,1111 Pereira DL, Pires FR, Lopes MA, Carlos R, Wright JM, Patel P, et al. Clinical, demographic, and radiographic analysis of 82 patients affected by florid osseous dysplasia: an international collaborative study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(2):250-7. http://dx.doi.org/10.1016/j.0000.2016.04.013
https://doi.org/10.1016/j.0000.2016.04.0...
,2020 Koklu HK, Cankal DA, Bozkaya S, Ergun G, Baris E. Florid cemento-osseous dysplasia: Report of a case documented with clinical, radiographic, biochemical and histological findings. J Clin Exp Dent. 2013;5(1):e58-61. http://dx.doi.org/10.4317/jced.50854
https://doi.org/10.4317/jced.50854...
,2121 Sarmetro DJ, Brito Metro BV, de Medeiros AM, da Silveira EJ. Severe florid cemento-osseous dysplasia: a case report treated conservatively and literature review. Oral Maxillofac Surg. 2013;17(1):43-6. http://dx.doi.org/10.1007/s10006-012-0314-0
https://doi.org/10.1007/s10006-012-0314-...
].

Elective treatment, such as prosthodontic rehabilitation or orthodontic treatment among patients with CODs is little reported in the literature. In a clinical case of fibrous dysplasia, a normal response of dysplastic bone to orthodontic forces has been reported [2222 Eskandarloo A, Yousefi F. CBCT findings of periapical cemento-osseous dysplasia: A case report. Imaging Sci Dent. 2013;43(3):215-8. http://dx.doi.org/10.5624/isd.2013.43.3.215
https://doi.org/10.5624/isd.2013.43.3.21...
]. Successful cases of orthodontic treatment with no tooth extraction in young patients with FCOD have also been described [1212 Minhas G, Hodge T, Gill, DS. Orthodontic treatment and cemento-osseous dysplasia: a case report. J Orthod. 2008;35(2):90-5. http://dx.doi.org/10.1179/146531207225022500
https://doi.org/10.1179/1465312072250225...
,1313 Sethusa MP, Khan MI. The orthodontic management of a patient presenting with cemento-osseous dysplasia. SADJ. 2009;64(3):120-4.]. A challenge in the orthodontic management of patients with COD occurs when tooth extraction is indicated. This procedure can result in the exposure of poorly vascularized sclerotic cemental masses in the oral cavity, which can lead to infection and consequent secondary osteomyelitis [11 Waldron CA. Fibro-osseous lesions of the jaw. J Oral Maxillofac Surg. 1985;43(4):249-62.,22 Mccarthy EF. Fibro-osseous lesions of the maxillofacial bones. Head Neck Pathol. 2013;7(1):5-10. http://dx.doi.org/10.1007/s12105-013-0430-7
https://doi.org/10.1007/s12105-013-0430-...
,88 Cavalcante MB, de Oliveira Lima AL, Júnior MA, Santos MB. Florid cemento-osseous dysplasia simultaneous the chronic suppurative osteomyelitis in mandible. J Craniofac Surg. 2016;27(8):2173-6. http://dx.doi.org/10.1097/SCS.0000000000003095
https://doi.org/10.1097/SCS.000000000000...
]. Pulp vitality tests should be carried out along with reinforcement of oral hygiene [1212 Minhas G, Hodge T, Gill, DS. Orthodontic treatment and cemento-osseous dysplasia: a case report. J Orthod. 2008;35(2):90-5. http://dx.doi.org/10.1179/146531207225022500
https://doi.org/10.1179/1465312072250225...
]. In the present case, no tooth extraction was performed during orthodontic treatment. The dentist stressed the need of rigorous oral hygiene control and performed pulp tests to confirm vitality.

During the orthodontic treatment, some changes in the radiographic pattern were observed. Progressive mineralization of the lesions close to the mandibular left second pre-molar and the incisors and canines were noticed. This change is expected because FCOD has different radiographic aspects that correspond to the different developmental stages of the lesion. In the osteolytic stage, a well-defined radiolucent area with loss of the lamina dura is observed. In the cementoblastic stage, radiopaque masses are seen in the radiolucent area due to mineralization (deposition of a cementum-like material). The final stage is characterized by a radiopaque mass in the lesion [55 de Noronha Santos Netto J, Machado Cerri J, Miranda AM, Pires FR. Benign fibroosseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(5):56-65. http://dx.doi.org/10.1016/j.oooo.2012.05.022
https://doi.org/10.1016/j.oooo.2012.05.0...
,77 Köse TE, Köse OD, Karabas HC, Erdem TL, Özcan I. Findings of florid cemento-osseous dysplasia: a report of three cases. J Oral Maxillofac Res. 2013;4(4):1-6. http://dx.doi.org/10.5037/jomr.2013.4404
https://doi.org/10.5037/jomr.2013.4404...
,1111 Pereira DL, Pires FR, Lopes MA, Carlos R, Wright JM, Patel P, et al. Clinical, demographic, and radiographic analysis of 82 patients affected by florid osseous dysplasia: an international collaborative study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(2):250-7. http://dx.doi.org/10.1016/j.0000.2016.04.013
https://doi.org/10.1016/j.0000.2016.04.0...
,1515 MacDonald DS. Maxillofacial fibro-osseous lesions. Clin Radiol. 2015;70:25-36. http://dx.doi.org/10.1016/j.crad.2014.06.022
https://doi.org/10.1016/j.crad.2014.06.0...
]. Thus, the radiographic changes observed from 2006 to 2017, during and after orthodontic management, represent the usual developmental stages of the lesion.

Cone-beam computed tomography provides images from the axial, sagittal and frontal planes, and is indicated to evaluate the location and extent of the lesion [1919 Delai D, Bernardi A, Felippe GS, Da Silveira Texeira C, Felippe WT, Santos Felippe MC. Florid cemento-osseous dysplasia: a case of misdiagnosis. J Endod. 2015;41(11):1923-6. http://dx.doi.org/10.1016/j.joen.2015.08.016
https://doi.org/10.1016/j.joen.2015.08.0...
,2323 Colella G, Itro A, Perillo L, Cannavale R. Orthodontic movement of impacted cuspid in fibrodysplastic bone: a case report. Bone. 2010;46(1):248-50. http://dx.doi.org/10.1016/j.bone.2009.08.049
https://doi.org/10.1016/j.bone.2009.08.0...
,2424 Yildirim E, Bağlar S, Ciftci ME, Ozcan E. Florid cemento-osseous dysplasia: a rare case report evaluated with cone-beam computed tomography. J Oral Maxillofac Pathol. 2016; 20(2):329. http://dx.doi.org/10.4103/0973-029X.185930
https://doi.org/10.4103/0973-029X.185930...
]. Buccal and lingual expansion as well as a relationship with the anatomic structure was easily identified in the current case. Buccal expansion in the area of the mandibular left second pre-molar was observed. Lingual expansion of cortical bone in the mandibular left lateral incisor and canine area was also observed. Small expansions are observed in FCOD lesions, however expansions over 4 cm, with rapid growth without association with familial pattern have been recently reported [2525 Raubenheimer EJ, Noffke CE, Boy SC. Osseous dysplasia with gross jaw expansion: a review of 18 lesions. Head Neck Pathol. 2016;10(4):437-43. http://dx.doi.org/10.1007/s12105-016-0720-y
https://doi.org/10.1007/s12105-016-0720-...
].

CONCLUSION

The clinical case presented herein showed that changes in FCOD might take place over a period of time. Calcification and cortical expansion were observed in the imaging exams on the course of the follow-up. Surveillance of individuals with FCOD is highly encouraged in order to monitor the lesion’s clinical behavior.

Acknowledgments

This work was supported by the National Council for Scientific and Technological Development (CNPq), the Ministry of Science and Technology, Brazil (grant number: #309322/2015-4).This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001.

How to cite this article

  • Kato CNAO, Sampaio JDA, Amaral TMP, Abreu LG, Brasileiro CB, Mes quita RA. Oral management of a patient with cemento-osseous dysplasia: a case report. RGO, Rev Gaúch Odontol. 2019;67:e20190012. http://dx.doi.org/10.1590/1981-86372019000123574

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Publication Dates

  • Publication in this collection
    06 May 2019
  • Date of issue
    2019

History

  • Received
    29 Apr 2018
  • Reviewed
    15 June 2018
  • Accepted
    30 Oct 2018
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