Resumos
São relatados os casos de 19 pacientes com distrofia miotônica. São discutidos alguns aspectos clínicos e para-clínicos da doença: eletroforese e imunoeletroforese de proteínas do sôro, eletrocardiograma, eletrencefalograma, radiografia de crânio e pneumencefalograma. Os resultados apresentados foram comparados àqueles da literatura.
Some clinical and laboratorial data in 19 patients with myotonic dystrophy are reported. The results of electrophoresis of serum proteins, X-ray of skull, pneumoencephalogramm and electromyogramm are similar to those reported by other authors. Electrocardiographic studies disclosed: left or right anterior hemiblock in 37,50% of the patients; rythm disturbances in 12,50%, and other alterations included supra-ventricular extrassystoles, right branck block and disturbances in intra-ventricular conduction. The results of serum protein immuno-elecrophoresis were as follows: IgA — normal in 61,25%, increased in 18,75% and decreased in 12,50%; IgM — normal in 43,75%, increased in 37,50% and decreased in 18,75%; IgG — normal in 31,25%, increased in 25% and decreased in 43,75%. Abnormalities of immunoglobulins were found to be mainly in IgG fractions, but also in IgA and IgM. Although IgC was significantly decreased in our patients we found other abnormalities of immunoglobulins with no definite pattern.
Distrofia miotônica. Aspectos clínico-laboratoriais em 19 casos
Myotonic dystrophy: some clinical and laboratorial data in 19 cases
Milberto ScaffI; Ana Maria C. TsanaclisII; José Antonio LevyIII
IClínica Neurológica (Prof. H. M. Canelas) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo: Assistente
IIClínica Neurológica (Prof. H. M. Canelas) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo: Residente
IIIClínica Neurológica (Prof. H. M. Canelas) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo: Docente-Livre
RESUMO
São relatados os casos de 19 pacientes com distrofia miotônica. São discutidos alguns aspectos clínicos e para-clínicos da doença: eletroforese e imunoeletroforese de proteínas do sôro, eletrocardiograma, eletrencefalograma, radiografia de crânio e pneumencefalograma. Os resultados apresentados foram comparados àqueles da literatura.
SUMMARY
Some clinical and laboratorial data in 19 patients with myotonic dystrophy are reported. The results of electrophoresis of serum proteins, X-ray of skull, pneumoencephalogramm and electromyogramm are similar to those reported by other authors. Electrocardiographic studies disclosed: left or right anterior hemiblock in 37,50% of the patients; rythm disturbances in 12,50%, and other alterations included supra-ventricular extrassystoles, right branck block and disturbances in intra-ventricular conduction. The results of serum protein immuno-elecrophoresis were as follows: IgA normal in 61,25%, increased in 18,75% and decreased in 12,50%; IgM normal in 43,75%, increased in 37,50% and decreased in 18,75%; IgG normal in 31,25%, increased in 25% and decreased in 43,75%. Abnormalities of immunoglobulins were found to be mainly in IgG fractions, but also in IgA and IgM. Although IgC was significantly decreased in our patients we found other abnormalities of immunoglobulins with no definite pattern.
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Clínica Neurológica Faculdade de Medicina da Universidade de São Paulo Caixa Postal 3461 01000 São Paulo, SP Brasil.
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Datas de Publicação
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Publicação nesta coleção
12 Abr 2013 -
Data do Fascículo
Set 1974