Reply to the letter regarding the article entitled: “Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol”

Respostaà carta referente ao artigo intitulado: “Acessoà reabilitação após o AVC no Brasil (estudo AReA): protocolo de estudo multicêntrico”

Dear editor,

We appreciate Montanaro's¹ interest in our article “Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol”² and the opportunity to emphasize the goal of the AReA study, to investigate access to post-stroke rehabilitation within the first 6 months after discharge from public hospitals.² Access is defined as the opportunity to utilize healthcare services at the ideal time for the rehabilitation process, regardless of an individual's needs.³

A recent review of stroke guidelines for the care of people with stroke conducted by the World Stroke Organization Guideline Committee highlighted the need of rehabilitation provided not only by multidisciplinary but also by interdisciplinary teams, to provide comprehensive care for people with stroke. The teams should offer coordinated care, staffed by physicians, nurses, physiotherapists, occupational therapists, speech-language therapists, social workers, and nutritionists with expertise in stroke rehabilitation, recovery, and return to work.⁴ As stated in our manuscript, we absolutely agree with this approach: “current guidelines recommended that subjects with stroke should be assessed by a multidisciplinary team within 24 to 48 hours after admission and referred to a rehabilitation program immediately after discharge.”⁵

For this reason, we included questions about referrals to physical therapists, physiatrists, speech therapists, neurologists, psychologists, occupational therapies, and nutritionists (Table 1).² The first five questions are repeated in regard to referrals for each of these professionals, as stated in the line highlighted in gray, below the fifth question. In addition, the kind of rehabilitation service is asked in question 6. All responses will be collected and analyzed. We expect that the results of the AReA study will contribute to the situational understanding about access to multidisciplinary care in Brazil, which may be useful to guide public health policies to reduce the general and specific barriers to this kind of care in different Brazilian regions. We think that the participation of 22 centers distributed by five Brazilian regions is one of the main strengths of the AReA Study.

We also agree about the advantages of including tools to properly assess functionality in all its domains. Convinced about the central role of functionality as the primary outcome of the rehabilitation process, the AReA research group extensively discussed tool selection during the design phase of this protocol. Considering the (1) time for application of multiples tools that demand training for proper and standardizing application, (2) limitation of physical space and resources, and (3) the aim of the present study, we decided to include two validated tools: the NIH Stroke Scale, a standardized scale that provides assessment of neurological impairments, and the modified Rankin Scale that addresses disability will be used to characterize the patients included in the study.⁶

Detailed evaluation of the impact of stroke on metrics of body function and structure, activity and participation according to the International Classification of Functioning, Disability and Health (ICF)⁷ would certainly be part of another important study, with a different research question, demanding other design and methods. The protocol of such a study would require an increased length in the duration of interviews and physical examinations, compared with the AReA protocol. We expect that results from the present protocol will be able to guide the design of new studies in this field. Importantly, we also hope that results from the AReA study provide an alert to the relevance of studies in this field, and the need of funding for this kind of research.

Barriers to inclusion in a comprehensive study about the impact of stroke, such as difficulties in accessible transportation for patients with disabilities and the need of physical help from caregivers to attend sessions, may lead to bias if patients who can comply with the protocol schedule are also those with greater social support and economic conditions. For instance, caregivers may be available to accompany individuals with stroke to attend outpatient consults that include short interviews, but not long assessments. This, and other limitations for participation in rehabilitation studies have been documented by several studies in Brazil and in other countries.⁸ Advances in digital health may contribute to overcome physical barriers but will also request access to the internet and ability to communicate by means of computers or smartphones. We suggest that these variables be taken into consideration during the design of future studies about the impact of stroke.

References

• ¹
  Montanaro VVA. Letter to “Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol”. Arq Neuropsiquiatr 2023;81:701-702
• ²
  Cacho RO, Moro CHC, Bazan R, et al; AReA Study Group. Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol. Arq Neuropsiquiatr 2022;80(10):1067-1074. Doi: 10.1055/s-0042-1758558
  » https://doi.org/10.1055/s-0042-1758558
• ³
  Sanchez RM, Ciconelli RM. Conceitos de acessoà saúde. Rev Panam Salud Publica 2012;31(03):260-268
• ⁴
  Mead GE, Sposato LA, Sampaio Silva G, et al. A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization. Int J Stroke 2023;18(05):499–531. Doi: 10.1177/17474930231156753
  » https://doi.org/10.1177/17474930231156753
• ⁵
  ClinicalGuidelines for strokemanagement 2017. Stroke Foundation; 2017. https://informme.org.au/guidelines/living-clinical-guidelinesfor-stroke-management
  » https://informme.org.au/guidelines/living-clinical-guidelinesfor-stroke-management
• ⁶
  Cincura C, Pontes-Neto OM, Neville IS, et al. Validation of the National Institutes of Health Stroke Scale, modified Rankin Scale and Barthel Index in Brazil: the role of cultural adaptation and structured interviewing. Cerebrovasc Dis 2009;27(02):119–122. Doi: 10.1159/000177918
  » https://doi.org/10.1159/000177918
• ⁷
  WHO. World Health Organization. International Classification of Functioning, Disability, and Health. 2003. https://who.int
  » https://who.int
• ⁸
  Silva TRD, Luvizutto GJ, Martins LG, et al. Barriers to patient recruitment in a poststroke neurorehabilitation multicenter trial in Brazil. Braz J Med Biol Res 2023;56:e12326. Doi: 10.1590/1414-431X2023e12326
  » https://doi.org/10.1590/1414-431X2023e12326

Publication Dates

• Publication in this collection
  21 Aug 2023
• Date of issue
  2023

History

• Received
  18 June 2023
• Accepted
  20 June 2023