Abstract
Mechanisms of immune protection against the asexual blood stage infection by Plasmodium falciparum are reviewed. Recent studies of two independent lines of research developed at the Institute Pasteur, in humans and primate infections clearly indicate an obligatory interaction of antibodies and effector cells to express the anti-parasitic effect.
malaria; protective immunity; IgG isotypes; protective antibodies
Mechanisms of immune protection in the asexual blood stage infection by Plasmodium falciparum: analysis by in vitro and ex-vivo assays
Jurg Gysin1
Pierre Druilhe2
Luiz Pereira da Silva2
Institut Pasteur, Laboratoire d'immunoparasitologie, Cayenne, Guyane Française
Institut Pasteur, Département d'Immunologie, Paris, France
Mechanisms of immune protection against the asexual blood stage infection by Plasmodium falciparum are reviewed. Recent studies of two independent lines of research developed at the Institute Pasteur, in humans and primate infections clearly indicate an obligatory interaction of antibodies and effector cells to express the anti-parasitic effect.
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Publication Dates
-
Publication in this collection
04 June 2009 -
Date of issue
1992