Dengue type 2 outbreak in the south of the State of Bahia, Brazil: laboratorial and epidemiological studies

Nogueira, Rita M. R.; Miagostovich, Marize P.; Schatzmayr, Hermann G.; Moraes, Gerusa C.; Cardoso, Floriene M. A.; Ferreira, Janete; Cerqueira, Vera; Pereira, Manuel

doi:10.1590/S0036-46651995000600006

Abstracts

During March 1994 cases of a exanthematic acute disease were reported in the municipalities of Itagemirim, Eunápolis and Belmonte, state of Bahia. Dengue fever was confirmed by serology (MAC-ELISA) and by dengue virus type 2 isolation, genotype Jamaica. Signs and symptoms of classic dengue fever were observed with a high percentual of rash (73.8%) and pruritus (50.5%). Major haemorrhagic manifestations were unfrequent and only bleeding gum was reported. Dengue virus activity spreaded rapidly to important tourism counties like Porto Seguro, Ilhéus, Santa Cruz de Cabrália, Prado, Alcobaça and others, representing a risk for the spreading of dengue virus into the country and abroad.

Dengue virus type 2; Outbreak; Bahia

Em março de 1994, casos de uma doença exantemática foram notificados nos municípios de Itagimirim, Eunápolis e Belmonte, sul da Bahia. Infecção por dengue foi confirmada por sorologia (MAC-ELISA) e pelo isolamento de virus dengue tipo 2 (genotipo Jamaica). Sinais e sintomas de dengue clássico foram observados com um alto percentual de exantema (73,8%) e prurido (50,5%). Manifestações hemorrágicas não foram importantes e apenas casos de gengivorragia foram descritos. A atividade dos virus dengue espalhou-se rapidamente para importantes áreas de turismo da região, tais como Porto Seguro, Ilhéus, Santa Cruz de Cabrália, Prado, Alcobaça e outros, representando um risco da dispersão do virus para outras regiões do país e exterior.

EPIDEMIOLOGY

Dengue type 2 outbreak in the south of the State of Bahia, Brazil: laboratorial and epidemiological studies

Surto de dengue tipo-2 no sul do estado da Bahia, Brasil: estudos laboratoriais e epidêmicos

Rita M. R. Nogueira^I; Marize P. Miagostovich^I; Hermann G. Schatzmayr^I; Gerusa C. Moraes^II; Floriene M. A. Cardoso^II; Janete Ferreira^II; Vera Cerqueira^III; Manuel Pereira^III

^ILaboratory of Flavivirus, Department of Virology, IOC/FIOCRUZ, Av. Brasil 4365, 21040-360 - Rio de Janeiro, Brasil

^IICentral Laboratory, Secretary of Health of Bahia

^IIIEpidemiological Surveillance Division, Secretary of Health of Bahia

SUMMARY

During March 1994 cases of a exanthematic acute disease were reported in the municipalities of Itagemirim, Eunápolis and Belmonte, state of Bahia. Dengue fever was confirmed by serology (MAC-ELISA) and by dengue virus type 2 isolation, genotype Jamaica. Signs and symptoms of classic dengue fever were observed with a high percentual of rash (73.8%) and pruritus (50.5%). Major haemorrhagic manifestations were unfrequent and only bleeding gum was reported. Dengue virus activity spreaded rapidly to important tourism counties like Porto Seguro, Ilhéus, Santa Cruz de Cabrália, Prado, Alcobaça and others, representing a risk for the spreading of dengue virus into the country and abroad.

Keywords: Dengue virus type 2; Outbreak; Bahia.

RESUMO

Em março de 1994, casos de uma doença exantemática foram notificados nos municípios de Itagimirim, Eunápolis e Belmonte, sul da Bahia. Infecção por dengue foi confirmada por sorologia (MAC-ELISA) e pelo isolamento de virus dengue tipo 2 (genotipo Jamaica). Sinais e sintomas de dengue clássico foram observados com um alto percentual de exantema (73,8%) e prurido (50,5%). Manifestações hemorrágicas não foram importantes e apenas casos de gengivorragia foram descritos. A atividade dos virus dengue espalhou-se rapidamente para importantes áreas de turismo da região, tais como Porto Seguro, Ilhéus, Santa Cruz de Cabrália, Prado, Alcobaça e outros, representando um risco da dispersão do virus para outras regiões do país e exterior.

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

ACKNOWLEDGMENTS

The authors are greatfull to Dr. Maria José C. Oliveira and Marli Cordeiro from Fusam/PE.

Financial support: This work was supported by CNPq and Fundação Banco do Brasil.

Recebido para publicação em 03/10/1995.

Aceito para publicação em 01/11/1995.

Supported by CNPq and Fundação Banco do Brasil.

1. BURKE, D.S.; NISALAK, A.; JOHNSON, D.E. & SCOTT, R.M. - A prospective study of dengue infection in Bangkok. Amer. J. trop. Med. Hyg., 38: 172-180, 1988.
2. CLARKE, D.H. & CASALS, J. - Techniques for hemagglutination and hemagglutination-inhibition with arthropode-born virus. Amer. J. trop. Med. Hyg., 7: 561-573, 1958.
3. Epidemiological Surveillance Division, Secretary of Health of Bahia. DEVISA. Relatório Anual, 1994
4. GUBLER, D.J.; KUNO, G.; SATHER, G.E.; VELEZ, M. & OLIVER, A. - Use of mosquito cell cultures and specific monoclonal antibodies in surveillance for dengue viruses. Amer. J. trop. Med. Hyg., 33: 158-165, 1984.
5. KLIKS, S.C.; NIMMANITYA, S.; NISALAK, A. & BURKE, D.S. - Evidence that maternal dengue antibodies are important in the development of dengue haemorrhagic fever in infants. Amer. J. trop. Med. Hyg., 38: 411-419, 1988.
6. KUNO, G.; GOMEZ, I. & GUBLER, D.J. - Detecting artificial anti-dengue IgM immune complexes using an enzyme - linked immunosorbent assay. Amer. J. trop. Med. Hyg., 36: 153-159, 1987.
7. NOGUEIRA, R.M.R.; MIAGOSTOVICH, M.P.; LAMPE, E. & SCHATZMAYR, H.G. - Isolation of dengue type 2 in Rio de Janeiro. Mem. Inst. Oswaldo Cruz., 85: 253, 1990.
8. NOGUEIRA, R.M.R.; MIAGOSTOVICH, M.P.; LAMPE, E. et al. - Dengue epidemic in the state of Rio de Janeiro, Brazil. 1990-1: co-circulation of dengue 1 and dengue 2 serotypes. Epidem. Infect., 111: 163-170, 1993.
9. PINHEIRO, F.P. - Dengue in the Americas 1980-1987. Epidem. Bull. Pan Amer. Hlth. Org., 10: 1-8, 1989.
10. SCHATZMAYR, H.G.; NOGUEIRA, R.M.R.; ROSA, A.P.A.T. - An outbreak of dengue virus at Rio de Janeiro-1986. Mem. Inst. Oswaldo Cruz, 81: 245-246, 1986.
11. SOUZA, R.W.; CUNHA, R.V.; MIAGOSTOVICH, M.P. et al. - An outbreak of dengue in the state of Ceará, Brazil. Mem. Inst. Oswaldo Cruz., 90: 345-346, 1995.

Publication Dates

Publication in this collection
22 Sept 2006
Date of issue
Dec 1995

History

Accepted
01 Nov 1995
Received
03 Oct 1995

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. BURKE, D.S.; NISALAK, A.; JOHNSON, D.E. & SCOTT, R.M. - A prospective study of dengue infection in Bangkok. Amer. J. trop. Med. Hyg., 38: 172-180, 1988.

[2] 2. CLARKE, D.H. & CASALS, J. - Techniques for hemagglutination and hemagglutination-inhibition with arthropode-born virus. Amer. J. trop. Med. Hyg., 7: 561-573, 1958.

[3] 3. Epidemiological Surveillance Division, Secretary of Health of Bahia. DEVISA. Relatório Anual, 1994

[4] 4. GUBLER, D.J.; KUNO, G.; SATHER, G.E.; VELEZ, M. & OLIVER, A. - Use of mosquito cell cultures and specific monoclonal antibodies in surveillance for dengue viruses. Amer. J. trop. Med. Hyg., 33: 158-165, 1984.

[5] 5. KLIKS, S.C.; NIMMANITYA, S.; NISALAK, A. & BURKE, D.S. - Evidence that maternal dengue antibodies are important in the development of dengue haemorrhagic fever in infants. Amer. J. trop. Med. Hyg., 38: 411-419, 1988.

[6] 6. KUNO, G.; GOMEZ, I. & GUBLER, D.J. - Detecting artificial anti-dengue IgM immune complexes using an enzyme - linked immunosorbent assay. Amer. J. trop. Med. Hyg., 36: 153-159, 1987.

[7] 7. NOGUEIRA, R.M.R.; MIAGOSTOVICH, M.P.; LAMPE, E. & SCHATZMAYR, H.G. - Isolation of dengue type 2 in Rio de Janeiro. Mem. Inst. Oswaldo Cruz., 85: 253, 1990.

[8] 8. NOGUEIRA, R.M.R.; MIAGOSTOVICH, M.P.; LAMPE, E. et al. - Dengue epidemic in the state of Rio de Janeiro, Brazil. 1990-1: co-circulation of dengue 1 and dengue 2 serotypes. Epidem. Infect., 111: 163-170, 1993.

[9] 9. PINHEIRO, F.P. - Dengue in the Americas 1980-1987. Epidem. Bull. Pan Amer. Hlth. Org., 10: 1-8, 1989.

[10] 10. SCHATZMAYR, H.G.; NOGUEIRA, R.M.R.; ROSA, A.P.A.T. - An outbreak of dengue virus at Rio de Janeiro-1986. Mem. Inst. Oswaldo Cruz, 81: 245-246, 1986.

[11] 11. SOUZA, R.W.; CUNHA, R.V.; MIAGOSTOVICH, M.P. et al. - An outbreak of dengue in the state of Ceará, Brazil. Mem. Inst. Oswaldo Cruz., 90: 345-346, 1995.