Abstract
Aqueous solutions of the molluscicidal latex of Euphorbia splendens are irritant to the rabbit eye in concentrations higher than 0.35% and to the rabbit skin in concentrations higher than 0.5%. Although this irritant potential does not proclude its use as a molluscicide, special precautions are recommended for hanbdling and application of the product and the hazard of skin tumor-promoting potencial should be carefully investigated before its use for schistosomiasis vector control.
Euphorbia splendens; plants molluscicide; schistosomiasis; skin irritation; eye irritation; toxicology
Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye
J. C. B. R. Freitas1
O. A. F. Presgrave1
F. F. Fingola1
M. A. C. Menezes1
M. C. Vasconcellos2
V. T. Schall2
F. J. R. Paumgartten1
Instituto Nacional de Controle de Qualidade em Saúde, Departamento de Farmacologia e Toxicologia, Rio de Janeiro, Brasil
Instituto Oswaldo Cruz, Departamento de Biologia, Rio de Janeiro, Brasil
Aqueous solutions of the molluscicidal latex of Euphorbia splendens are irritant to the rabbit eye in concentrations higher than 0.35% and to the rabbit skin in concentrations higher than 0.5%. Although this irritant potential does not proclude its use as a molluscicide, special precautions are recommended for hanbdling and application of the product and the hazard of skin tumor-promoting potencial should be carefully investigated before its use for schistosomiasis vector control.
Full text available only in PDF format.
Texto completo disponível apenas em PDF.
Publication Dates
-
Publication in this collection
24 June 2009 -
Date of issue
1991
