| Bipolar disorder |
Does the risk of developing dementia increase with the number of episodes in patients with depressive disorder and in patients with bipolar disorder? |
Kessing and Andersen (2004) |
The risk of dementia seems to increase with the number of episodes in depressive and bipolar affective disorders. |
| Plasma beta-amyloid peptides levels: a pilot study in bipolar depressed patients |
Piccinni (2012) |
Changes in plasma levels of different Aβ peptides might represent increase of the risk for cognitive decline in bipolar patients, such as AD. |
| Epigenetic modifications in frontal cortex from Alzheimer’s disease and bipolar disorder patients. |
Rao et al. (2012) |
Brains from BD and AD patients showed epigenetic changes in global DNA methylation related to neuroinflammation, synaptic integrity, neuroprotection and arachidonic acid metabolism. |
| Depression |
Depression and Risk for Alzheimer Disease: Systematic Review, Meta-analysis, and Metaregression Analysis |
Ownby et al. (2006) |
There is a high relationship between depressive symptoms and depression as a risk factor for the development of AD. |
| Prevalence of depression among older Americans: the Aging, Demographics and Memory Study |
Steffens et al. (2009) |
Individuals with dementia had among the highest prevalence of current depression. |
| Contribution of Depression to Cognitive Impairment and Dementia in Older Adults |
Potter and Steffens (2007) |
The prevalence of depression is highly in most dementias. In AD may be less intense. |
| The risk of developing depression when suffering from neurological diseases |
Thielscher et al. (2013) |
51.4% of patients developed depression, one year after the diagnosis of the AD. |
| Late-life depression and risk of vascular dementia and Alzheimer’s disease: systematic review and meta-analysis of community-based cohort studies |
Diniz et al. (2013) |
Association between late-life depression with the development of AD. |
| Increased Hippocampal Plaques and Tangles in Patients with Alzheimer Disease with a Lifetime History of Major Depression |
Rapp et al. (2006) |
Was found that of a lifetime history of depression, is associated the presence of a higher number of neuritic plaques and neurofibrillary tangles the hippocampus of the patients with AD. |
| Plasma amyloid β, depression, and dementia in community-dwelling elderly |
Direk et al. (2013) |
The presence of a higher number of neuritic plaques and neurofibrillary may be present in patients with depression without AD. Depression may also be associated with the accumulation of these plaques in elderly individuals |
| Serum amyloid beta protein in young and elderly depression: a pilot study. |
Kita et al. (2009) |
Serum Abeta40/42 ratio was higher in depressive patients. |
| Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunction. |
Rosenberg et al. (2011) |
Impairment in executive functions, were more severe in patients with depression and anxiety. People with features of depressive symptoms also associated with mild cognitive impairment, was found an increased risk for the development of AD. |
| Schizophrenia |
Dementia in middle-aged patients with schizophrenia |
Nicolas et al. (2014) |
Identified 14 schizophrenic patients with dementia among 96 elderly, but only two were diagnosed with likely AD. |
| A common brain network links development, aging, and vulnerability to disease |
Douaud et al. (2014) |
Suggested a common spatial pattern of abnormalities in a brain network in AD and schizophrenia. |
| Dysregulation of neural calcium signaling in Alzheimer disease, bipolar disorder and schizophrenia |
Berridge (2013) |
Dysregulation of the Ca(2+) signaling pathway is responsible for development of neural diseases such as Alzheimer disease, bipolar disorder and schizophrenia. |
| Bipolar disorder, depression and Schizophrenia |
Severe psychiatric disorders in mid-life and risk of dementia in late-life (age 65-84 years): a population based case-control study. |
Zilkens et al. (2014) |
Severe depression, bipolar disorder, schizophrenia and alcoholic dependency disorder in mid-life are important risk factors for AD in the late-life. |
| Bipolar disorder and depression |
Affective disorders and risk of developing dementia: systematic review |
da Silva et al. (2013) |
Increased risk for dementia in individuals with depression, and bipolar disorder |
