ADHERE66 Fonarow GC, Adams KF Jr, Abraham WT, Yancy CW, Boscardin WJ; ADHERE Scientific Advisory Committee, Study Group, and Investigators. Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis. JAMA. 2005;293(5):572-80. Fonarrow |
2005 |
Multicêntrico Internacional (33 046) |
Multicêntrico (32.229) |
Idade, Clínicas Laboratoriais (4) |
MIH/ 0,75 |
AHFI 1919 Auble TE, Hsieh M, Gardner W, Cooper GF, Stone RA, McCausland JB, et al. A prediction rule to identify low-risk patients with heart failure. Acad Emerg Med. 2005;12(6):514-21. Auble |
2005 (derivação) 2008 (validação) |
Multicêntrico Nacional (33 533) |
Amostra aleatorizada (8384) |
Demográficas Clínicas Laboratoriais Testes diagnósticos não invasivos (21) |
MIH/ 0,59 |
GWTG-HF 2121 Peterson PN, Rumsfeld JS, Liang L, Albert NM, Hernandez AF, Peterson ED, et al; American Heart Association Get With the Guidelines-Heart Failure Program. A validated risk score for in-hospital mortality in patients with heart failure from the American Heart Association get with the guidelines program. Circ Cardiovasc Qual Outcomes. 2010;3(1):25-32.Peterson |
2010 |
Comunitário Multicêntrico Internacional (27 850) |
Comunitário Multicêntrico (11 933) |
Demográficas Clínicas Laboratoriais Comorbidades (7) |
MIH / 0,75 |
EFFECT 2222 Lee DS, Austin PC, Rouleau JL, Liu PP, Naimark D, Tu JV. Predicting mortality among patients hospitalized for heart failure: derivation and validation of a clinical model. JAMA. 2003;290(19):2581-7. Lee |
2003 |
Multicêntrico Nacional (2624) |
Comunitário Multicêntrico (1407) |
Demográficas Clínicas Laboratoriais Comorbidades (10) |
Mortalidade aos 30 dias/0,79 Mortalidade a um ano/0,76 |
OPTIMIZE-HF 2020 O'Connor CM, Abraham WT, Albert NM, Clare R, Gattis Stough W, Gheorghiade M, et al. Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Am Heart J. 2008;156(4):662-73. O'Connor |
2008 |
Registo Multicêntrico Internacional (4402) |
OPTIME CHF (949) y ESCAPE (433) |
Demográficas Clínicas Laboratoriais Comorbidades (13) |
Mortalidade a 60-90 dias/0,72 |
OPTIMIZE-HF 55 Abraham WT, Fonarow GC, Albert NM, Stough WG, Gheorghiade M, Greenberg BH, et al; OPTIMIZE-HF Investigators and Coordinators. Predictors of in-hospital mortality in patients hospitalized for heart failure: insights from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). J Am Coll Cardiol. 2008;52(5):347-56. Abraham |
2008 |
Registo Multicêntrico Internacional (37 548) |
Bootstrapping interno Ensaio ADHERE (181 830) |
Demográficas Clínicas Laboratoriais Disfunção sistólica (7) |
MIH/ 0,74 |
OPTIME CHF 2323 Felker GM, Leimberger JD, Califf RM, Cuffe MS, Massie BM, Adams KF Jr, et al. Risk stratification after hospitalization for decompensated heart failure. J Card Fail. 2004;10(6):460-6. Felker |
2004 |
Multicêntrico Internacional (949) |
Bootstrapping interno |
Demográficas Clínicas Laboratoriais (5) |
Mortalidade a 60 dias/0,77 |
Otawa 2424 Stiell IG, Clement CM, Brison RJ, Rowe BH, Borgundvaag B, Aaron SD, et al. A risk scoring system to identify emergency department patients with heart failure at high risk for serious adverse events. Acad Emerg Med. 2013;20(1):17-26 Stiell |
2013 |
Comunitário Multicêntrico Nacional (507) |
Bootstrapping interno |
Clínicas Laboratoriais (10) |
Mortalidade aos 30 dias ou evento não fatal aos 14 dias/BNP 0,77, não BNP 0,75 |
EHRMG 2525 Lee DS, Stitt A, Austin PC, Stukel TA, Schull MJ, Chong A, et al. Prediction of heart failure mortality in emergent care: a cohort study. Ann Intern Med. 2012;156(11):767-75, W-261, W-262. Lee |
2012 |
Comunitário Multicêntrico Nacional (7433) |
Comunitário Multicêntrico (5.158) |
Clínicas Laboratoriais Comorbidades (10) |
Mortalidade 7 dias/0,8 |