Acessibilidade / Reportar erro

Effects of bariatric surgery on the metabolic syndrome

BACKGROUND: Morbid obesity is a state of insulin resistance associated with excess of visceral fat, which is involved in the development of metabolic syndrome. In obesity, conservative therapies promote improvement of the metabolic syndrome, but weight regain is common. The Roux-en-Y gastric bypass results in weight loss, more significant and sustained, besides promoting improvement of the metabolic syndrome, that is a risk factor for development of systemic atherosclerotic disease. AIM: To demonstrate that bariatric surgery promotes the reversal of the metabolic syndrome. METHODS: The study included 74 obese patients underwent to Roux-en-Y gastric bypass by laparoscopy. Were evaluated with weight measurement, waist circumference, body mass index, blood pressure and blood glucose levels, triglycerides, total cholesterol and HDL fraction, preoperative and over six months after operation. To compare means it was used the non-parametric Friedman test and the Wilcoxon test, level of significance p <0.05. RESULTS: There were 52 women and 22 men with mean age of 34.6 years. The range of follow-up was six months. The average body mass index preoperatively was 42 and six months after operation was 29.6. It was confirmed a statistically significant difference between the moments in all the quantitative variables analyzed. CONCLUSION: It can be inferred that bariatric surgery is an effective method of weight loss and normalization of parameters used in the diagnosis of metabolic syndrome.

Obesity; Metabolic syndrome; Diabetes mellitus; Bariatric surgery


Colégio Brasileiro de Cirurgia Digestiva Av. Brigadeiro Luiz Antonio, 278 - 6° - Salas 10 e 11, 01318-901 São Paulo/SP Brasil, Tel.: (11) 3288-8174/3289-0741 - São Paulo - SP - Brazil
E-mail: revistaabcd@gmail.com