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Diffuse neurofibroma - an uncommon cause of alopecia* * Work performed at the Department of Dermatology, Portuguese Institute of Oncology Francisco Gentil (IPOLFG) - Lisbon, Portugal.

Neurofibroma difuso - uma causa rara de alopécia

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.

Alopecia; Neurofibroma; Scalp


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