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TROPICAL/INFECTOPARASITARY DERMATOLOGY • An. Bras. Dermatol. 96 (05) • 2021 • https://doi.org/10.1016/j.abd.2021.01.003   copy

Disseminated mucocutaneous trichosporonosis in a patient with histiocytic sarcoma☆ ☆ How to cite this article: Robles-Tenorio A, Rivas-López RA, Bonifaz A, Tarango-Martínez VM. Disseminated mucocutaneous trichosporonosis in a patient with histiocytic sarcoma. An Bras Dermatol. 2021;96:595-597. ,☆☆ ☆☆ Study conducted at the Hospital General de Occidente, Zapopan, México.

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Abstract

Trichosporon asahii is the causal agent of trichosporonosis. Patients with immunosuppression or hematological malignancies are at higher risk of infection. Skin and mucosal involvement appear as fast-growing papulonodular lesions and necrotic ulcers. Internal organ dissemination is lethal. Therapeutic success depends on the underlying disease. Here, the authors present the first case of disseminated mucocutaneous trichosporonosis in a patient with a post-mortem diagnosis of histiocytic sarcoma, a rare and aggressive haematolymphoid neoplasm. Regretfully, death occurred despite treatment with liposomal amphotericin B and supportive measures, showcasing the fatality of both diseases.

KEYWORDS
Hematologic neoplasms; Histiocytic sarcoma; Trichosporon; Trichosporonosis; Ulcer

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