Generalized granuloma annulare after pneumococcal vaccination<sup>,</sup>

García-Gil, Miguel Fernando; Álvarez-Salafranca, Marcial; Martínez García, Alejandro; Ara-Martín, Mariano

doi:10.1016/j.abd.2020.05.009

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Case Report • An. Bras. Dermatol. 96 (1) • Jan-Feb 2021 • https://doi.org/10.1016/j.abd.2020.05.009 copy

Generalized granuloma annulare after pneumococcal vaccination^☆ ☆ How to cite this article: García-Gil MF, Álvarez-Salafranca M, Martínez García A, Ara-Martín M. Generalized granuloma annulare after pneumococcal vaccination. An Bras Dermatol. 2021;96:59-63. ^,^☆☆ ☆☆ Study conducted at the Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

Granuloma annulare may be caused by multiple triggers. Among these are vaccinations, which have been described as an infrequent cause of granuloma annulare. The authors report the first case of generalized granuloma annulare associated with pneumococcal vaccination in a 57-year-old woman, who presented cutaneous lesions 12 days after vaccination.

KEYWORDS
Case reports; Granuloma annulare; Vaccination

Authors	Year	Vaccine	Dose	Sex	Age	Localized/generalized	Latency time	Treatment	Resolution	Revaccination recurrence
Houcke-Bruge C et al.	2001	BCG	1 dose	Male	3 years	Generalized	1 month	No	Complete, 3 months
		BCG	1 dose	Female	2 years	Location remote from vaccination site	2 months	No	Complete, 3 months
Kakurai M et al.	2001	BCG	1 dose	Male	12 years	Generalized	5 days	No	Complete, 7 months
Nagase K et al.	2011	BCG	1 dose	Male	5 months	Generalized	1 month	Moisturizer, 3 months	Complete, 3 months
Lee SW et al.	2011	BCG	1 dose	Female	3 months	Generalized	1 month	Topical corticosteroids, 1 month	Complete, 1 month
Nomiyama T et al.	2013	BCG	1 dose	Female	6 months	Generalized	1 month	Topical corticosteroids 1 month	Complete, 1 month
Yoon NY et al.	2014	BCG	1 dose	Male	3 months	Generalized	7 weeks	Ceftriaxone for 8 days and prophylactic hydroxyzine for 3 weeks	Complete, 3 weeks
Yang SY et al.	2018	BCG	1 dose	Male	3 months	Generalized	2 months	No	Complete, 18 months
Wolf F et al.	1998	Hepatitis B virus	4 doses (0 months, 1 month, 2 months, 12 months)	Female	51 years	Generalized	1 month after the last vaccine	Dapsone 50 mg/day 4 months	Complete, 4 months (subsequent recurrence)	Revaccination at 5 years (latency time of 3 weeks)
Criado PR et al.	2004	Hepatitis B virus	2 doses (0 months, 1 month)	Female	58 years	Generalized	2 months after the last vaccine	Topical corticosteroids	Partial improvement, 3 months
Baykal C et al.	2002	Tetanus	1 dose	Female	6 years	Generalized	2 months	Triamcinolone acetonide 10 mg/mL every 4 weeks, intralesional (3 sessions)	Complete, 3 months (subsequent recurrence)	Revaccination (latency time of 3 days)
Baskan EB et al.	2005	Diphtheria and tetanus toxoid	1 dose	Female	8 years	Generalized	1 week	Topical corticosteroids	No improvement
Suzuki T et al.	2014	Influenza	1 dose	Female	76 years	Generalized	1 month	No	No follow-up

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[1] * Corresponding author. E-mail: miguelgarciagil@outlook.com (M.F. García-Gil).