Chronic mucocutaneous anogenital herpes: series of ten cases and literature review

Calbucci, Karina Baruel de Camargo Votto; Veasey, John Verrinder

doi:10.1016/j.abd.2021.03.014

Acessibilidade / Reportar erro

Brasil

Anais Brasileiros de Dermatologia

Español English

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

Tropical/Infectoparasitary Dermatology • An. Bras. Dermatol. 97 (3) • May-Jun 2022 • https://doi.org/10.1016/j.abd.2021.03.014 copy

Chronic mucocutaneous anogenital herpes: series of ten cases and literature review^☆ ☆ Study conducted at the Dermatology Clinic, Santa Casa de Misericórdia de São Paulo, SP, Brazil.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

Anogenital herpes is one of the most prevalent sexually transmitted infections worldwide. It has several clinical manifestations, from cases of primary herpes infection to recurrent forms, among them chronic mucocutaneous herpes. This presentation is rare, characterized by a duration of more than four weeks, usually associated with immunosuppression and resistance to classic anti-herpetic treatment. The present study presents a series of ten cases of chronic mucocutaneous herpes with a discussion about its clinical, laboratory, and therapeutic aspects.

Keywords
Antiviral agents; Genital diseases, female; Genital diseases, male; Herpes genitalis; Herpes simplex

Characteristics of the patients				Characteristics of the lesions		Diagnosis		Treatment
Case	Age	Sex	Comorbidities	Time of lesion	Location	Tzanck test	Biopsy (IHC)	Antiviral	Via (VO/EV)	Daily dose	Time until cure
1	15	M	Type 1 Diabetes mellitus	3 months	Genital	NP	NP	Acyclovir	PO	1,200 mg	4 weeks
2	52	F	HIV (CD4 430 cells/mm³)	1 month	Genital	NP	+	Valacyclovir	PO	1,000 mg	10 weeks (+ surgery)
3	51	F	HIV (CD4 6 cells/mm³)	1 month	Genital	+	NP	Acyclovir	IV	2,400 mg	4 weeks
4	15	F	Chronic mucocutaneous candidiasis	1 month	Gluteus	+	NP	Valacyclovir	PO	1,000 mg	6 weeks
5	59	M	Albinism	1 month	Genital	+	NP	Acyclovir	PO	4,000 mg	8 weeks
6	46	M	Alcohol abuse	1 month	Genital	+	NP	Acyclovir	PO	1,200 mg	6 weeks
7	58	M	HIV (CD4 187 cels/mm³)	18 months	Genital	NP	+	Acyclovir	PO	4,000 mg	Abandoned treatment
8	30	F	HIV (CD4 128 cells/mm³)	3 months	Anal	+	NP	Acyclovir	IV	2,400 mg	Death
9	41	M	HIV (CD4 112 cells/mm³)	9 months	Genital	+	-	Acyclovir	VO	1,000 mg	Abandoned treatment
10	30	F	HIV (CD4 51 cells/mm³)	3 months	Genital	NP	+	Foscarnet	IV	5,280mg	3 weeks

Sociedade Brasileira de Dermatologia Av. Rio Branco, 39 18. and., 20090-003 Rio de Janeiro RJ, Tel./Fax: +55 21 2253-6747 - Rio de Janeiro - RJ - Brazil
E-mail: revista@sbd.org.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] ∗Corresponding author. E-mail:kbc.votto@gmail.com (K.B. Calbucci).

Brasil

Brasil

Chronic mucocutaneous anogenital herpes: series of ten cases and literature review☆ ☆ Study conducted at the Dermatology Clinic, Santa Casa de Misericórdia de São Paulo, SP, Brazil.

Abstract

Chronic mucocutaneous anogenital herpes: series of ten cases and literature review^☆ ☆ Study conducted at the Dermatology Clinic, Santa Casa de Misericórdia de São Paulo, SP, Brazil.