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Recurrent skin ulcer cross-repair and sensory reconstruction in a WRN gene mutational patient* * Work conducted at the Xiangya Hospital of Central South University, Xiangya Road, Changsha, China.

Abstract:

A 37-year-old man complained of a refractory posterior malleolar ulceration on his left ankle. He was diagnosed with Werner syndrome according to the progeroid clinical features and genetic testing. To approach the ulceration, a free flow-through right anterolateral thigh perforator flap with anterolateral thigh cutaneous nerve was harvested. One year later, he was readmitted due to a new ulceration on his right ankle. We harvested the left anterolateral thigh perforator flap with anterolateral thigh cutaneous nerve to reconstruct the defect. After one more year of follow-up, there was no recurrence of ulcers, and the sensation of the flap recovered partially after 6 months. We conclude that free flow-through anterolateral thigh perforator flap is a feasible choice for the repair of foot ulcers in Werner syndrome.

Keywords:
Perforator flap; Reconstructive surgical procedures; Skin ulcer; Werner syndrome

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