Comparative dermatology: elephantiasis nostra in verrucous form comparable to coral

Abstracts

Demonstra-se quadro raro de Elefantíase Nostra, na sua forma verrucosa, no dorso de pé de homem de 80 anos por episódios prévios de erisipela de repetição. As lesões confluentes vegetantes e difusas em dorso de pé são comparáveis aos corais Trumpet Coral (Caulastrea curvata)

Elefantíase; Erisipela; Streptococcus pyogenes

ICONOGRAPHY

Comparative dermatology: elephantiasis nostra in verrucous form comparable to coral^*

Lana Bezerra Fernandes^I; Luiz Fernando Fróes Fleury Junior^II

^IResident MD in dermatology at the Hospital das Clfnicas da Universidade Federal de Goias (UFGO), Goiania (GO), Brazil; Assistant Professor in the Department of Tropical Medicine and Dermatology at IPTSP (UFG), Goiania, Brazil

^IIMaster's Degree in dermatology awarded by the University of São Paulo (USP), São Paulo, Brazil

^{Mailing address}

ABSTRACT

Study of a rare case of Elephantiasis Nostra in verrucous form on the dorsum of the foot of an 80 year-old male with a history of recurrent erysipelas infection. The vegetant, confluent lesions on the foot resemble Trumpet Coral (Caulastrea curvata).

Keywords: Elephantiasis; Erysipelas; Streptococcus pyogenes

Erysipelas is an acute non-necrotizing dermohypodermal infection, usually caused by beta-hemolytic Streptococcus pyogenes, especially Lancefield group A. The infection is characterized by sudden onset of fever and chills lasting between 12 and 24 hours¹. It is an infectious lymphangitis marked by a red skin-rash with a sharply demarcated raised edge, spread along the lymph capillary network and also affecting the lymph nodes. ² This occurs not only in non-infectious lymphangitis, but also in the recurrent episodes of erysipelas suffered by elderly or immunodepressed patients, due to lymphatic impairment. The exudate of protein, fibrin and figurata elements, as well as endothelial damage causing thrombosis of the lymphatic trunk, eventually leads to edema and lymphedema ³. About 85% of lymphedemas are due to recurrent lymphangitis, and therefore this diagnosis should always be considered when the dermatological symptoms are associated with lymphatic impairment (lymphedema, lymphangitis). Chronic lymphedema caused by erysipelas can lead to deformities typical of Elephantiasis Nostra, ⁴ often inviting comparison with natural coral, especially the Trumpet Coral (Caulastrea curvata) species.

CASE REPORT

An 80-year-old agricultural worker, phototype V, presented lesions with a mossy, verrucous appearance. Exophytic and agglomerated lesions measuring 0.5 to 5 cm were observed on the back of the right foot and toes (Figure 1). Patient cited a number of untreated erysipelas episodes over 20 years. Histopathology showed fibrosing dermatitis with perivascular lymphocytic infiltrate associated with substantial epidermal hyperplasia. No granulomas, acidfast bacilli (AFB), fungi or signs of malignancy were discovered in the material examined. Negative culture for fungi.

DISCUSSION

Erysipelas is an infectious lymphangitis which in over 80% of cases is located in the lower limbs, and is affected by a patient's predisposition to chronic lymphedema and obesity. The diagnosis is essentially clinical, based on the presence of plaque inflammation associated with fever, lymphangitis, lymphadenopathy and leukocytosis. Elephantiasis Nostra, which can result from chronic lymphedema caused by recurrent erysipelas, is a rare, chronic and deforming disorder, characterized by verrucous hyperkeratosis and papillomatosis of the epidermis, associated with fibrosis of the dermis and subcutaneous tissue ³. Since the disease presents as widespread, vegetating and verrucous lesions affecting the whole of the back of the foot and toes, causing elephantiasis-type deformity, it is often compared with coral, particularly the species known as Trumpet Coral (Caulastrea curvata) (see Figure 2). ⁴ Underwater coral reefs grow by first establishing a skeleton structure for each new polyp. They then secrete a rigid calcium carbonate skeleton and, when the organism dies, the structure remains in place. New coral grows on the old skeleton to form reefs similar to the lesions presented in cases of erysipelas.

REFERENCES

Received on 23.12.2010

Approved by the Advisory Board and accepted for publication on 14.01.11.

Conflict of interest: None

Financial funding: None

References

• 1. Bisno AL, Stevens D: Streptococcal infections of skin and soft tissues. N Engl J Med. 1996;334:240-5.
• 2. Dupuy A, Benchikhi H, Roujeau JC, Bernard P, Vaillant L, Chosidow O, et al. Risk factors for erysipelas of the leg (cellulitis): case control study. Br Med J. 1999;318:1591-4.
• 3. Mayall RC, Mayall ACDG, Pereira VCSR, Araújo BES, Gracio EM, Preussler MM. Erysipelas and lymphangitis. Lymphology. 1996;29(Suppl):307-9.
• 4. Vallarelli AFA, Silva VMCF, Souza EM. Dermatologia comparativa (parte VI). An Bras Dermatol. 1999;74:641-2
• ⁵ Department of Primary Industries and Fisheries 2008, Annual status report 2007. Queensland Coral Fishery, Department of Primary Industries and Fisheries, Brisbane. [cited 2011 Jun 10]. Available from: http://www.environment.gov.au/coasts/fisheries/qld/east-coast-finfish/pubs/east-coast-finfish-submission-2007.pdf

*

Study undertaken at the Hospital das Clfnicas da Universidade Federal de Goias, Goiania (GO), Brazil.

Publication Dates

• Publication in this collection
  27 Sept 2011
• Date of issue
  Aug 2011

History

• Received
  23 Dec 2010
• Accepted
  14 Jan 2011