Necrose gordurosa subcutânea do recém-nascido: manifestações clínicas de
                  dois casos

A Necrose Gordurosa Subcutânea do Recém-Nascido é uma paniculite incomum com poucos casos descritos na literatura médica. A doença acomete recém-nascidos a termo ou pós-termo, com saúde geral normal. Relatamos dois casos de recém-nascidos acometidos pela doença. Um deles já apresentava lesões ao nascer. Também discutimos o uso da punção para auxílio diagnóstico.

Biópsia por agulha fina; necrose gordurosa; Recém-nascido

Autoria

Milena Pires de Campos Luciano Gomes Mailing address: Milena Pires de Campos Luciano Gomes, Rua Borges Lagoa, 508 - Vila Clementino, 04038-001 - São Paulo - SP, Brazil. Email: milena_epm@yahoo.com.br

Federal University of São Paulo, Paulista Medical School, São Paulo, SP, BrazilFederal University of São PauloBrazilSão Paulo, SP, BrazilFederal University of São Paulo, Paulista Medical School, São Paulo, SP, Brazil

Adriana Maria Porro

Federal University of São Paulo, Paulista Medical SchoolFederal University of São PauloFederal University of São Paulo, Paulista Medical School

Federal University of São Paulo, Paulista Medical School, dermatology department, São Paulo, SP, BrazilFederal University of São PauloBrazilSão Paulo, SP, BrazilFederal University of São Paulo, Paulista Medical School, dermatology department, São Paulo, SP, Brazil

Milvia Maria Simões da Silva Enokihara

Federal University of São Paulo, Paulista Medical School, pathology department, dermatology departments, São Paulo, SP, BrazilFederal University of São PauloBrazilSão Paulo, SP, BrazilFederal University of São Paulo, Paulista Medical School, pathology department, dermatology departments, São Paulo, SP, Brazil

Marcos César Floriano

Federal University of São Paulo, Paulista Medical School, department of dermatology, São Paulo, SP, BrazilFederal University of São PauloBrazilSão Paulo, SP, BrazilFederal University of São Paulo, Paulista Medical School, department of dermatology, São Paulo, SP, Brazil

Mailing address: Milena Pires de Campos Luciano Gomes, Rua Borges Lagoa, 508 - Vila Clementino, 04038-001 - São Paulo - SP, Brazil. Email: milena_epm@yahoo.com.br

SCIMAGO INSTITUTIONS RANKINGS

Federal University of São Paulo, Paulista Medical SchoolFederal University of São PauloFederal University of São Paulo, Paulista Medical School

Figuras

Figuras (5)

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FIGURE 1
Case 1. Areas of atrophy on the left arm and left masseter region. Hardened nodule in the distal region of the left arm. Residual lesions.

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FIGURE 2
Case 2. Edema and erythema on the left arm

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FIGURE 3
Case 2 – Fine-needle aspiration puncture (FNAP). FNAP product stained by the papinicolaou method. A close-knit grouping of histiocytes, lymphocytes and adipose cells, was noted (100x)

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FIGURE 4
Case 2 - Fine-needle aspiration puncture. FNAP presenting, in detail, a grouping of histiocytic cells to the left and an adipocyte containing one giant multinucleated cell to the right (Papanicolaou 400x)

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FIGURE 5
Case 2 – Histological exam. Subcutaneous adipose tissue reveals, to the left, a giant strange body multinucleated cell. To the right, necrotic adipocytes (without nucleus) can be observed, as well as cholesterol crystals in the center of the photo (needle-shaped fissures in radial arrangement) (HE 400x)

FIGURE 1 Case 1. Areas of atrophy on the left arm and left masseter region. Hardened nodule in the distal region of the left arm. Residual lesions.

FIGURE 2 Case 2. Edema and erythema on the left arm

FIGURE 3 Case 2 – Fine-needle aspiration puncture (FNAP). FNAP product stained by the papinicolaou method. A close-knit grouping of histiocytes, lymphocytes and adipose cells, was noted (100x)

FIGURE 4 Case 2 - Fine-needle aspiration puncture. FNAP presenting, in detail, a grouping of histiocytic cells to the left and an adipocyte containing one giant multinucleated cell to the right (Papanicolaou 400x)

FIGURE 5 Case 2 – Histological exam. Subcutaneous adipose tissue reveals, to the left, a giant strange body multinucleated cell. To the right, necrotic adipocytes (without nucleus) can be observed, as well as cholesterol crystals in the center of the photo (needle-shaped fissures in radial arrangement) (HE 400x)

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E-mail: revista@sbd.org.br

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Necrose gordurosa subcutânea do recém-nascido: manifestações clínicas de dois casos

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[1] Mailing address: Milena Pires de Campos Luciano Gomes, Rua Borges Lagoa, 508 - Vila Clementino, 04038-001 - São Paulo - SP, Brazil. Email: milena_epm@yahoo.com.br