Acessibilidade / Reportar erro
Tropical/Infectoparasitary Dermatology • An. Bras. Dermatol. 96 (2) • Mar-Apr 2021 • https://doi.org/10.1016/j.abd.2020.07.008   copy

Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease☆ ☆ How to cite this article: Garcia LC, Vale ECS, Ferrari ML, Faria LDC. Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease. An Bras Dermatol. 2021;96:228-30. ,☆☆ ☆☆ Study conducted at Dermatology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patient treated with infliximab for Crohn's disease, who presented diarrhea, weight loss, abdominal pain, fever, and subcutaneous erythematous nodules that evolved with spontaneous fluctuation and ulceration. With the finding of alcohol-resistant bacilli and Mycobacterium tuberculosis DNA in a cutaneous fragment, through polymerase chain reaction, the diagnosis of gummatous tuberculosis was confirmed, probably secondary to hematogenous dissemination from an intestinal focus.

KEYWORDS
Crohn's disease; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; Molecular target therapy; Skin tuberculosis

Sociedade Brasileira de Dermatologia Av. Rio Branco, 39 18. and., 20090-003 Rio de Janeiro RJ, Tel./Fax: +55 21 2253-6747 - Rio de Janeiro - RJ - Brazil
E-mail: revista@sbd.org.br
Acompanhe os números deste periódico no seu leitor de RSS