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Deep cutaneous ulcers and sinus formation in an immunocompetent adult How to cite this article: Zhou Q, Zhu K. Deep cutaneous ulcers and sinus formation in an immunocompetent adult. An Bras Dermatol. 2019;94:744-6. ,☆☆ ☆☆ Study conducted at the Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Zhejiang, China.

Abstract

This report describes a case of unusual deep skin ulcers with tortuous sinus tract formation in an immunocompetent woman. She was initially diagnosed with a Staphylococcus aureus skin infection and histopathologically diagnosed with pyoderma gangrenosum. However, culture from the deep end of ribbon gauze inserted into the subcutaneous sinus tract revealed shiny, light-yellow mucoid colonies, which were identified as Cryptococcus neoformans var. grubii. She was treated with fluconazole for nine months and completely healed. Cryptococcosis is an opportunistic infection caused by variants of C. neoformans species. Cutaneous manifestations of cryptococcosis are quite divergent, rarely occurring as deep skin ulcers with sinus formation.

KEYWORDS
Cryptococcosis; Infection; Skin ulcer

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