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Neovascularization of the retina in SC hemoglobinopathy and * * Resumo da tese apresentada à Faculdade de Medicina da Universidade de São Paulo, para a obtenção do Título de Doutor em Medicina na Área de Oftalmologia. Tese orientada pelo prof. Sérgio Lustosa da Cunha e aprovada em abril de 1992. vitreous hemorrhage

SUMMARY

We studied 31 eyes with proliferative sickle retinopathy at Goldberg's stage III (9 eyes) and IV (22 eyes), from 20 SC patients. The mean age was 31.7 years (range: 19-55, SD: 9,74). The size, number per eye and circunferential extention were analysed in 98 sea fan lesions (SF). We did a correlation between the two last variables and the presence of vitreous hemohrrage (VH). When we divided the circunferential extention in 15 degrees intervals, we concluded that the greater the interval, the greater the chance of an eye to present VH (p=0.0476). The circunferential involvement of 30º or less was present in 9,09% of the eyes in the stage IV and in 55.5% of the eyes in stage III, and the sarne involvement larger than 30º occurred in 90.91% in stage IV and in 44.45% in stage III (p=0.0195). From the 98 SFs, 31.63% measured 30º or less and more than a half (51.01%) measured 45º or less. The number of SFs is not related to VH, but we concluded that in eyes with SFs extending circunferentially more than 30º have a greater chance to present with VH (stage IV) and that the SFs are small lesions, usually with 7 or 8mm of extension.

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