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Standardization of pattern electroretinograms by alternate reversion in normal volunteers

PURPOSE: To standardize recordings of pattern electroretinograms (PERG) in normal human subjects. METHODS: The standardization followed the model proposed by the International Organization of Eletroretinography and was specific for the laboratory of evoked potentials of the Department of Neurology, Faculty of Medical Sciences, State University of Campinas. Two types of stimuli were used, one of 30 minutes of arch of visual angle and another of 60 minutes of arch of visual angle. RESULTS: In all patients a positive wave, defined internationally as P50, and a negative, called N95, were obtained without interferences. The normal range for latency, amplitude and duration of each wave was obtained. There were significative differences in amplitude, latency and duration of P50 and N95 waves among the several age groups. There was an increase in latency and a decrease in amplitude with increasing age. No significative differences were found among the variables comparing different stimuli, sex or when eyes were compared with each other. CONCLUSIONS: The standardization of pattern electroretinograms yield reproductibility of results and the possibility of further comparative studies.

Electroretinography; Evoked potentials; visual; Optic nerve; Reproducibility of results


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