Resolution of post-trauma conjunctival inclusion cyst using 0.5% timolol maleate eyedrops

A 70-year-old woman presented with a conjunctival cyst after a towel hit her left eye (LE) 2 weeks prior. She was initially prescribed with retinyl acetate, aminoacids, methionine, and chloramphenicol ointment as well as a lubricant eyedrop for 7 days; these did not provide resolution. Ophthalmological examination revealed a translucent conjunctival inclusion cyst surrounded by several small vessels in the LE temporal side (Figure 1A). Following administration with 0.5% timolol maleate eyedrops twice daily, the inclusion cyst completely resolved 2 weeks later. Figure 1B shows the conjunctiva of the LE 50 days after the patient’s initial presentation.

Although rare, acquired conjunctival cysts(¹) may develop due to local trauma. Surgical excision is usually indicated(²). Before excision, timolol maleate was initially prescribed, hypothesizing that the vessels surrounding the cyst might possess beta-adrenergic receptors similar to pyogenic granulomas and capillary hemangiomas(³,⁴), which are effectively treated with beta-blockers.

• Funding: This study received no specific financial support.

REFERENCES

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  » https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186631/

Publication Dates

• Publication in this collection
  27 May 2024
• Date of issue
  2024

History

• Received
  13 Nov 2023
• Accepted
  02 Feb 2024