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Clinical validation of a computerized psychophysical test for color vision and contrast sensitivity

Purpose: To determine the reliability of TwoDocs compu-terized test for the evaluation of color vision and contrast sensitivity in normal adults. Methods: Thirty normal volunteers aged from 20 to 30 years (mean 23.3 years) had their color vision and contrast sensitivity tested by a new computerized test (TwoDocs test). Informed consent was obtained from all participants before testing. Inclusion criteria were: absence of visual com-plaints, absence of previous ophthalmic surgery, absence of family history of ophthalmologic diseases, best corrected visual acuity for near and distance of 20/20. Tests with the Farnsworth-Munsell 100-hue (FM-100) test for color vision assessment and the Pelli-Robson chart for contrast sensitivity measurement were also performed on the same visit, and both were considered gold standards for clinical validation. Results: The results of contrast sensitivity obtained with the Pelli-Robson chart and TwoDocs test showed agreement of 100%. Color vision results obtained with the TwoDocs test showed a strong trend to overestimate color vision classification when compared with FM-100. Conclusion: The new computerized psychophysical TwoDocs test showed a high sensitivity and specificity for contrast sensitivity measurement and can be a useful clinical tool in ophthalmology practice for this visual task. Color vision classification obtained with the TwoDocs test showed a low specificity when compared with FM-100. One possible reason for this overestimation is the computer monitor used to generate the color pattern. Additional studies in patients with disorders in color vision should be done for understan-ding the usefulness of this method better in clinical color vision assessment.

Color vision; Contrast sensitivity; Clinical assessment


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