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Bioceramic cement in the filling of bone defects in rats1 1 Research performed at the Laboratory of Bases of Surgical Techniques, Faculty of Medicine, and the Laboratory of Biology, Faculty of Biology, Universidade Vale do Sapucaí (UNIVÁS), Pouso Alegre-MG, Brazil. Part of Master’s degree thesis, Professional Masters in Sciences Applied to Health. Tutor: Prof. José Dias da Silva Neto.

Abstract

Purpose

To evaluate PBS®MCIMMO cement in the filling of bone defects.

Methods

Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups.

Results

In all comparisons, significance was observed for group 2 (p = 0.0014–0.0026).

Conclusion

The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.

Dental Implants; Immediate Dental Implant Loading; Guided Tissue Regeneration, Periodontal; Bone Substitutes; Rats

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