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A standard burn model using rats

Um modelo padronizado de queimaduras em ratos

Experimental burn models are always needed, being essential for burn research. In the present study, we describe a standard Fischer F-344 rat burn model, in which burns are produced with a heated brass bar. The animals were anesthetized with ketamine (90 mg/kg). After the burns, they were resuscitated with saline. Burns ranging from 26% to 30% of total body surface area resulted in a 62.5 % mortality rate after 25 days. This model is an additional option for those interested in burn research.

Burns; Disease Models, Animal


Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia https://actacirbras.com.br/ - São Paulo - SP - Brazil
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