Barushka et al.3535 Barushka O, Yaakobi T, Oron U. Effect of low-energy laser (He-Ne) irradiation on the process of bone repair in the rat tibia. Bone. 1995;16(1):47-55. https://doi.org/10.1016/s8756-3282(94)00006-9 https://doi.org/10.1016/s8756-3282(94)00...
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Tibia |
Gallium-aluminum-arsenide λ = 808 nm |
Five and six days postoperatively once a day for 2 minutes |
Nine, 10, 11, 12 and 15 days |
Histologic and Histomorphometric |
The laser favored the repair of fractures or acute defects in the bones |
Ninomiya; Ozawa3636 Nishisaka T, Ozawa H. Increase of bone volume by a nanosecond pulsed laser irradiation is caused by a decreased osteoclast number and an activated osteoblasts. Bone. 2007;40(1):140-8. https://doi.org/10.1016/j.bone.2006.07.026 https://doi.org/10.1016/j.bone.2006.07.0...
|
Femur |
Gallium-aluminum-arsenide λ = 1,064 nm |
10 minutes, twice a day |
One, three, five and seven days |
Histologic and Histomorphometric |
The laser increased in bone volume, trabecular thickness, mineral apposition rate, bone mineral density index |
Kazancioglu et al.2121 Kazancioglu HO, Ezirganli S, Aydin MS. Effects of laser and ozone therapies on bone healing in the calvarial defects. J Craniofac Surg. 2013;24(6):2141-6. https://doi.org/10.1097/SCS.0b013e3182a244ae https://doi.org/10.1097/SCS.0b013e3182a2...
|
Calvaria |
Gallium-aluminum-arsenide λ = 808 nm |
120 seconds a day, three days a week, for two weeks |
One month |
Histologic and Histomorphometric |
The laser increased bone formation compared to the control group |
Yildirimturk et al.3737 Yildirimturk S, Sirin Y, Soluk Tekkesin M, Gurler G, Firat D. The effects of low-level laser therapy on the healing of bone defects in streptozotocin-induced diabetic rats: a histological and morphometric evaluation. J Cosmet Laser Ther. 2017;19(7):397-403. https://doi.org/10.1080/14764172.2017.1341048 https://doi.org/10.1080/14764172.2017.13...
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Tibia |
Gallium-aluminum-arsenide λ = 820 nm |
Three times a week for four weeks |
Four weeks |
Histologic |
Beneficial effects on the healing of bone defects in diabetic conditions |
de Oliveira et al.2525 Moreira GS, Machado Alves PH, Esper LA, Sbrana MC, da Silva Dalben G, Neppelenbroek KH, Fraga de Almeida ALP. Effect of low-level laser on the healing of bone defects filled with autogenous bone or bioactive glass: in vivo study. Int J Oral Maxillofac Implants. 2018;33(1):169-74. https://doi.org/10.11607/jomi.5900 https://doi.org/10.11607/jomi.5900...
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Calvaria |
Gallium-aluminum-arsenide λ = 780 nm |
Immediately after surgery and at intervals of 48 and 96 hours |
21 and 30 days |
Radiographic, Histological, Immunohistochemistry and Immunofluorescence |
Favored bone repair |
Pinheiro et al.3838 Pinheiro AL, Soares LG, Marques AM, Canguss MC, Pacheco MT, Silveira L. Biochemical changes on the repair of surgical bone defects grafted with biphasic synthetic micro-granular HA + B-tricalcium phosphate induced by laser and LED phototherapies and assessed by Raman spectroscopy. Lasers Med Sci. 2017;32(3):663-72. https://doi.org/10.1007/s10103-017-2165-2 https://doi.org/10.1007/s10103-017-2165-...
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Tibia |
Gallium-aluminum-arsenide λ = 780 nm |
48-hour intervals for two weeks |
15 and 30 days |
Spectroscopy |
It improved the repair of bone defects grafted with the biomaterial by increasing the deposition of hydroxyapatite phosphate as marked by biochemical estimators |
Atasoy et al.3434 Atasoy KT, Korkmaz YT, Odaci E, Hanci H. The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing. Braz Oral Res 2017;31:e7. https://doi.org/10.1590/1807-3107BOR-2017.vol31.0007 https://doi.org/10.1590/1807-3107BOR-201...
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Tibia |
Gallium-aluminum-arsenide λ = 940 nm |
Immediately after suturing, two, four, six, eight, 10 and12 days after |
Four and eight weeks |
Histopathological |
It may not accelerate the bone repair process in the early and late stages compared to the control group without laser application |
Dereci et al.2323 Dereci O, Sindel A, Serap Toru H, Yce E, Ay S, Tozülu S. The comparison of the efficacy of blue light-emitting diode light and 980-nm low-level laser light on bone regeneration. J Craniofac Surg. 2016;27(8):2185-9. https://doi.org/10.1097/scs.0000000000003068 https://doi.org/10.1097/scs.000000000000...
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Calvaria |
Gallium-aluminum-arsenide λ = 980 nm |
5 minutes immediatelyafter surgeryand six days after |
21 days |
Histomorphometric |
Significantly increased bone regeneration in critical defects when compared to the control group |
Bosco et al.2222 Bosco AF, Faleiros PL, Carmona LR, Garcia VG, Theodoro LH, de Araujo NJ, Nagata MJ, de Almeida JM. Effects of low-level laser therapy on bone healing of critical-size defects treated with bovine bone graft. J Photochem Photobiol B. 2016;163:303-10. https://doi.org/10.1016/j.jphotobiol.2016.08.040 https://doi.org/10.1016/j.jphotobiol.201...
|
Calvaria |
Gallium-aluminum-arsenide λ = 660 nm |
Eight points around the defect and a central point immediately making the defect |
30 and 60 days |
Histologic and Histomorphometric |
Improved bone repair and accelerated the resorption of biomaterial particles |
Moreira et al.2525 Moreira GS, Machado Alves PH, Esper LA, Sbrana MC, da Silva Dalben G, Neppelenbroek KH, Fraga de Almeida ALP. Effect of low-level laser on the healing of bone defects filled with autogenous bone or bioactive glass: in vivo study. Int J Oral Maxillofac Implants. 2018;33(1):169-74. https://doi.org/10.11607/jomi.5900 https://doi.org/10.11607/jomi.5900...
|
Calvaria |
Gallium-aluminum-arsenide λ = 780 nm |
Four points around and one in the center, only once |
30 days |
Histomorphometric |
There was no increase in bone neoformation when associated with autogenous bone or bioactive glass |