Kim et al.2828 Kim KJ, Jang BW, Lee SK, Kim BK, Nam SL. A case of peripheral primitive neuroectodermal tumor of the ovary. Int J Gynecol Cancer. 2004;14(2):370-2. http://doi.org/10.1136/ijgc-00009577-200403000-00027. PMid:15086740. http://doi.org/10.1136/ijgc-00009577-200...
|
Right ovary |
18 |
Rapidly growing lower abdominal mass. CT revealed 16 × 13 cm-sized solid and cystic multi-lobulated mass in the pelvic cavity. |
Pelvic and para-aortic lymph nodes |
Right salpingo-oophorectomy, left ovary wedge resection, omentectomy, para-aortic and pelvic lymph node resection and chemotherapy, including taxol/carboplatin, pelvic cavity radiotherapy, followed by vincristine, actinomycin, cyclophosphamide, doxorubicin (VACA). Death after 10 months due to septic shock. |
Ateser et al.2929 Ateser G, Yildiz O, Leblebici C, et al. Metastatic primitive neuroectodermal tumor of the ovary in pregnancy. Int J Gynecol Cancer. 2007;17(1):266-9. http://doi.org/10.1111/j.1525-1438.2006.00761.x. PMid:17291265. http://doi.org/10.1111/j.1525-1438.2006....
|
Right ovary |
28 |
24th week of pregnancy, a 3-day history of generalized abdominal pain, nausea, and vomiting. Abdominal ultrasound showed a 24-week fetus and a multi-lobulated solid mass situated in the right lower abdominal quadrant extending from the pelvis up to the umbilicus. |
Para-aortic Lymph nodes |
Right salpingo-oophorectomy followed by chemotherapy including doxorubicin, cyclophosphamide, vincristine. The patient delivered at 37 weeks of gestation. She had extensive metastatic disease and was treated with chemotherapy and radiotherapy post-delivery. However, she declined further therapy and died due to progressive disease 13 months after the initial diagnosis. |
Kuk et al.3030 Kuk JY, Yoon SY, Kim MJ, Lee JW, Kim BG, Bae DS. A case of primitive neuroectodermal tumor of the ovary. Korean J Obstet Gynecol. 2012;55(10):777-81. http://doi.org/10.5468/KJOG.2012.55.10.777. http://doi.org/10.5468/KJOG.2012.55.10.7...
|
Right ovary |
32 |
Ovarian PNET was detected during her second Cesarean section. She had a past history of oophorectomy due to a huge mature solid teratoma in left ovary during her first Cesarean section. |
Bilateral internal iliac lymph nodes |
Right salpingoophorectomy and peritoneal mass excisional biopsy were performed followed by 8 cycles of multiple regimen chemotherapy with vincristine, doxorubicin, cyclophosphamide, and etoposide, ifosfamide (VDC/IE). She remained in complete remission with no evidence of disease 54 months from presentation. |
Ahadi et al.3131 Ahadi R, Tavakol N, Babaheidarian P, Abbasi Y. Ovarian Primitive Neuroectodermal Tumor (PNET): a case report. GinPolMedProject. 2018;3(49):23-6.
|
Left ovary |
30 |
Pelvic pain and distention for less |
Para-aortic Lymph nodes |
Laparotomy for resection of tumor followed by Bleomycin, Cisplatin, and Etoposide based chemotherapy. However, she died two months later due to extensive metastatic disease before completing all the cycles of chemotherapy. |
than two weeks. Abdominopelvic CT scan revealed an irregular heterogeneous mass in the left adnexa with adhesion to the surrounding organs. |
Chao et al.2222 Chao X, Bi Y, Li L. Ovarian primary primitive neuroectodermal tumor: a review of cases at PUMCH and in the published literature. Orphanet J Rare Dis. 2019;14(1):147. http://doi.org/10.1186/s13023-019-1106-5. PMid:31217017. http://doi.org/10.1186/s13023-019-1106-5...
|
Right ovary |
67 |
Abdominal distention and changes in bowel habits over the previous 4 months. Ultrasonography revealed a pelvic mass of approximately 22 cm in diameter. Colonoscopy indicated sigmoid colon adhesions and stenosis |
Lymph nodes around the colon |
Tumor cytoreductive surgery with right salpingo-oophorectomy, appendectomy, infracolic omental excision, and partial excision of the sigmoid colon and small intestine. The patient refused further treatment and died 6 months after her initial symptoms. |
Index Case |
Both ovaries |
33 |
Left submandibular swelling of 1.5 months duration. History of bilateral ovarian PNET treated successfully with bilateral salpingo-oophorectomy and total hysterectomy followed by chemotherapy and was disease free for 2 years. |
Metastatic recurrence as left submandibular lymphadenopathy |
Patient immediately started on VAC + IE based combination chemotherapy following cytological diagnosis and has shown excellent response. She is currently receiving chemotherapy and has been kept on close follow-up. |