Abrahão, 2015 [66. Boström C, Elfving B, Dupré B, Opava CH, Lundberg IE, Jansson E. Effects of a one-year physical activity programme for women with systemic lupus erythematosus – a randomized controlled study. Sage Journals. 2016;25:602–16.] |
42 |
Intervention (n = 21) cardiovascular training Control group (n = 21) (usual care and information about the disease) |
03 months |
Quality of life |
The intervention group presented a significant improvement in the physical health and vitality aspect, in the general health aspect no significant differences were found (SF36 health survey questionnaire) |
Arriens, 2015 [99. Strand V, Petri M, Kalunian K, Gordon C, Wallace DJ, Hobbs K, et al. Epratuzumab for patients with moderate to severe flaring SLE: health-related quality of life outcomes and corticosteroid use in the randomized controlled ALLEVIATE trials and extension study SL0006. Rheumatology. 2014;53:502–11.] |
32 |
Intervention (n = 18) (supplementation with fish oil) Control group (n = 14) (placebo) |
06 months |
Quality of life |
The intervention group presented a significant improvement in the mental health and vitality aspect (SF36 health survey questionnaire) |
Boström, 2016 [77. Navarrete-Navarrete N, Peralta-Ramírez MI, Sabio JM, Martínez-Egea I, Santos-Ruiz A, Jiménez-Alonso J. Quality-of-life predictor factors in patients with SLE and their modification after cognitive behavioural therapy. Sage Journals. 2010;19:1632–9.] |
31 |
Intervention (n = 17) (physical activity) Control group (n = 14) (usual care) |
12 months |
Quality of life |
The intervention group had improved mental health, there was no significant improvement in the general health aspect (SF36 health survey questionnaire). |
Navarrete, 2010 [44. Shamekhi Z, Amani R, Habibagahi Z, Namjoyan F, Ghadiri A, Malehi AS. A Randomized, Double-blind, Placebo-controlled Clinical Trial Examining the Effects of Green Tea Extract on Systemic Lupus Erythematosus Disease Activity and Quality of Life. Phytother Res. 2017;31(7):1063–71.] |
45 |
Intervention (n = 21) (cognitive behavioral therapy) Control group (n = 24) (health care, moderate exercise, balanced diet and plenty of rest) |
15 months |
Quality of life |
The intervention group had a significant reduction in the level of depression, anxiety and daily stress and a significant improvement in QoL and somatic symptoms (SF36 health survey questionnaire). |
Navarrete et al, 2010 [88. Arriens C, Hynan LS, Lerman RH, Karp DR, Mohan C. Placebo-controlled randomized clinical trial of fish oil’s impact on fatigue, quality of life, and disease activity in systemic lupus erythematosus. Nutr J. 2015;14:82.] |
34 |
Intervention (n = 18) cognitive behavioral therapy Control group (n = 16) (usual care) |
15 months |
Quality of life |
The intervention group presented improvement in the level of physical function, vitality, general health perception andmental health (SF36 health survey questionnaire) |
Shamehki, 2017 [55. Abrahão MI, Gomiero AB, Peccin MS, Grande AJ, Trevisani VFM. Cardiovascular training vs. resistance training for improving quality of life and physical function in patients with systemic lupus erythematosus: a randomized controlled trial. Scand J Rheumatol. 2015:1–5.] |
68 |
Intervention (n = 32) (supplementation of green tea extract) Control group (n = 36) (placebo) |
03 months |
Quality of life |
The intervention group presented a significant increase in hrvitality and general health (SF36 health survey questionnaire). |
Strand, 2013 [1010. Carvalho MR, Sato EI, Tebexreni AS, Heidecher RT, Schenkman S, Neto TL. Effects of supervised cardiovascular training program on exercise tolerance, aerobic capacity, and quality of life in patients with systemic lupus erythematosus. Rev Arthritis & Rheumatism. 2005;53:838–44.] |
48 |
Intervention (n = 11) (epratuzumab 720mg/m2) Control group (n = 37) (placebo) |
12 months |
Quality of life |
The intervention group showed evident improvements in the mean SF-36 scores (SF36 health survey questionnaire). |